A Waterborne Outbreak of Escherichia coli O157:H7 Infections and Hemolytic Uremic Syndrome: Implications for Rural Water Systems1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Olsen, Sonja J. ; Miller, Gayle ; Breuer, Thomas ; Kennedy, Malinda ; Higgins, Charles ; Walford, Jim ; McKee, Gary ; Fox, Kim ; Bibb, William ; Mead, Paul
• Description:
  In the summer of 1998, a large outbreak of Escherichia coli O157:H7 infections occurred in Alpine, Wyoming. We identified 157 ill persons; stool from 71 (45%) yielded E. coli O157:H7. In two cohort studies, illness was significantly associated with drinking municipal water (town residents: adjusted odds ratio=10.1, 95% confidence intervals [CI]=1.8-56.4; visitors attending family reunion: relative risk=9.0, 95% CI=1.3-63.3). The unchlorinated water supply had microbiologic evidence of fecal organisms and the potential for chronic contamination with surface water. Among persons exposed to water, the attack rate was significantly lower in town residents than in visitors (23% vs. 50%, p<0.01) and decreased with increasing age. The lower attack rate among exposed residents, especially adults, is consistent with the acquisition of partial immunity following long-term exposure. Serologic data, although limited, may support this finding. Contamination of small, unprotected water systems may be an increasing public health risk.
• Subjects:
  Adult Child, Preschool Cohort Studies Diarrhea Disease Outbreaks Drinking Escherichia Coli Infections Escherichia Coli O157 Female Hemolytic-Uremic Syndrome Humans Infant Male Research Retrospective Studies Risk Factors Rural Population Water Microbiology Water Supply

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• Source:
  Emerg Infect Dis. 8(4):370-375.
• Document Type:
  Journal Article
• Place as Subject:
  Wyoming
• Volume:
  8
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:dacb594280a1467d57d5103ede4bd67407cbffd600fa84ba76a5fb5a10e911b1
• Download URL:
  https://stacks.cdc.gov/view/cdc/3063/cdc_3063_DS1.pdf
• File Type:
  [PDF - 406.00 KB ]