Effects of Varying Case Definition on Carpal Tunnel Syndrome Prevalence Estimates in a Pooled Cohort

Details

• Alternative Title:
  Arch Phys Med Rehabil
• Personal Author:
  Thiese, Matthew S. ; Gerr, Fred ; Hegmann, Kurt T. ; Harris-Adamson, Carisa ; Dale, Ann Marie ; Evanoff, Bradley ; Eisen, Ellen A. ; Kapellusch, Jay ; Garg, Arun ; Burt, Susan ; Bao, Stephen ; Silverstein, Barbara ; Merlino, Linda ; Rempel, David
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• Description:
  Objective ; To analyze differences in carpal tunnel syndrome (CTS) prevalence using a combination of electrodiagnostic studies (EDSs) and symptoms using EDS criteria varied across a range of cutpoints and compared with symptoms in both ≥1 and ≥2 median nerve–served digits. ; Design ; Pooled data from 5 prospective cohorts. ; Setting ; Hand-intensive industrial settings, including manufacturing, assembly, production, service, construction, and health care. ; Participants ; Employed, working-age participants who are able to provide consent and undergo EDS testing (N=3130). ; Interventions ; None. ; Main Outcome Measures ; CTS prevalence was estimated while varying the thresholds for median sensory latency, median motor latency, and transcarpal delta latency difference. EDS criteria examined included the following: median sensory latency of 3.3 to 4.1 milliseconds, median motor latency of 4.1 to 4.9 milliseconds, and median-ulnar sensory difference of 0.4 to 1.2 milliseconds. EDS criteria were combined with symptoms in ≥1 or ≥2 median nerve–served digits. EDS criteria from other published studies were applied to allow for comparison. ; Results ; CTS prevalence ranged from 6.3% to 11.7%. CTS prevalence estimates changed most per millisecond of sensory latency compared with motor latency or transcarpal delta. CTS prevalence decreased by 0.9% to 2.0% if the criteria required symptoms in 2 digits instead of 1. ; Conclusions ; There are meaningful differences in CTS prevalence when different EDS criteria are applied. The digital sensory latency criteria result in the largest variance in prevalence.
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• Subjects:
  • Adult
  • Carpal Tunnel Syndrome
  • Construction Industry
  • Electrodiagnosis
  • Female
  • Health Care Sector
  • Humans
  • Male
  • Manufacturing Industry
  • Median Nerve
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• Keywords:
  • Carpal tunnel syndrome
  • Diagnostic techniques and procedures
  • Electrodiagnosis
  • Prevalence
  • Rehabilitation
  • Standards
• Source:
  Arch Phys Med Rehabil. 2014; 95(12):2320-2326
• Pubmed ID:
  25175160
• Pubmed Central ID:
  PMC4342110
• Document Type:
  Journal Article
• Funding:
  R01-OH009712/OH/NIOSH CDC HHSUnited States/ ; T42/CCT810426-10/PHS HHSUnited States/ ; UL1 RR024992/RR/NCRR NIH HHSUnited States/ ; UL1 TR000448/TR/NCATS NIH HHSUnited States/ ; R01 OH009712/OH/NIOSH CDC HHSUnited States/
• Volume:
  95
• Issue:
  12
• Download URL:
  https://stacks.cdc.gov/view/cdc/30305/cdc_30305_DS1.pdf
• File Type:
  [PDF - 286.03 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b5be3298aacefd9fe79cfb6cfccb89d0587ea9bc77db8a7a45035ea87c99f1db