Details:

Alternative Title:
Nutr Cancer
Personal Author:
Chandran, Urmila ; McCann, Susan E. ; Zirpoli, Gary ; Gong, Zhihong ; Lin, Yong ; ... More +
Chandran, Urmila ; McCann, Susan E. ; Zirpoli, Gary ; Gong, Zhihong ; Lin, Yong ; Hong, Chi-Chen ; Ciupak, Gregory ; Pawlish, Karen ; Ambrosone, Christine B. ; Bandera, Elisa V. ; Less -
Description:
Limiting energy-dense foods, fast foods, and sugary drinks that promote weight gain is a cancer prevention recommendation, but no studies have evaluated intake in relation to breast cancer risk in African American (AA) women. In a case-control study with 1692 AA women (803 cases and 889 controls) and 1456 European American (EA) women (755 cases and 701 controls), odds ratios (OR) and 95% confidence intervals (CI) for risk were computed, stratifying for menopausal and estrogen receptor (ER) status. Among postmenopausal EA women, breast cancer risk was associated with frequent consumption of energy-dense foods (OR = 2.95; 95% CI: 1.66-5.22), fast foods (OR = 2.35; 95% CI: 1.38-4.00), and sugary drinks (OR = 2.05; 95% CI: 1.13-3.70). Elevated risk of ER+ tumors in EA women was associated with energy-dense (OR = 1.75; 95% CI: 1.14-2.69) and fast foods (OR = 1.84; 95% CI: 1.22-2.77). Among AA women, frequent fast food consumption was related to premenopausal breast cancer risk (OR = 1.97; 95% CI: 1.13-3.43), and with ER+ tumors. Energy adjustment attenuated risk estimates in AA women, while strengthening them among EA women. Frequent consumption of energy-dense and fast foods that have poor nutritive value appeared to increase breast cancer risk in AA and EA women, with differences by menopausal status and ER status.
Subject:
[+]
Adult
African American
African Americans
Aged
Article
Beverages
Body Mass Index
Breast Cancer
Breast Neoplasms
Case-Control Studies
Diet
Dietary Carbohydrates
Energy-dense
Energy Intake
European Continental Ancestry Group
Fast Foods
Female
Humans
Logistic Models
Middle Aged
Nutritive Sweeteners
Postmenopause
Race
Risk Factors
Surveys And Questionnaires
Weight Gain
Young Adult

Source:
Nutr Cancer. 66(7):1187-1199
Pubmed ID:
25265504
Pubmed Central ID:
PMC4201626
Document Type:
Journal Article ;
Funding:
U58 DP003931/DP/NCCDPHP CDC HHS/United States ; P30 CA072720/CA/NCI NIH HHS/United States ; P01 CA151135/CA/NCI NIH HHS/United States ; K22 CA138563/CA/NCI NIH HHS/United States ; P30CA072720/CA/NCI NIH HHS/United States ; ... More +
U58 DP003931/DP/NCCDPHP CDC HHS/United States ; P30 CA072720/CA/NCI NIH HHS/United States ; P01 CA151135/CA/NCI NIH HHS/United States ; K22 CA138563/CA/NCI NIH HHS/United States ; P30CA072720/CA/NCI NIH HHS/United States ; N01PC-2010-00027/PC/NCI NIH HHS/United States ; 1US58DP003931-01/DP/NCCDPHP CDC HHS/United States ; R01 CA100598/CA/NCI NIH HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f0ff799b992478c56ee45caee44b0c9a47902ab724bd425fad31f9c9b16dde96
File Type:

Supporting Files

• nihms624225.nxml

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