Biosynthesis of Fungal Indole Alkaloids

Details

• Alternative Title:
  Nat Prod Rep
• Personal Author:
  Xu, Wei ; Gavia, Diego J. ; Tang, Yi
• Description:
  This review provides a summary of recent research advances in elucidating the biosynthesis of fungal indole alkaloids. The different strategies used to incorporate and derivatize the indole/indoline moieties in various families of fungal indole alkaloids will be discussed, including tryptophan-containing nonribosomal peptides, polyketide-nonribosomal peptide hybrids, and alkaloids derived from other indole building blocks. This review also includes a discussion regarding the downstream modifications that generate chemical and structural diversity among indole alkaloids.
• Keywords:
  Fungi Indole Alkaloids Molecular Structure
• Source:
  Nat Prod Rep. 31(10):1474-1487
• Pubmed ID:
  25180619
• Pubmed Central ID:
  PMC4162825
• Document Type:
  Journal Article
• Funding:
  DP1 GM106413/GM/NIGMS NIH HHSUnited States/ ; R56 AI101141/AI/NIAID NIH HHSUnited States/ ; 1DP1GM106413/DP/NCCDPHP CDC HHSUnited States/ ; 1R56AI101141/AI/NIAID NIH HHSUnited States/
• Volume:
  31
• Issue:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:7786f909ce0b2d05460f344d5a51bf8cf9b7e75af1f89facd2f63fba98cf82f8
• Download URL:
  https://stacks.cdc.gov/view/cdc/30118/cdc_30118_DS1.pdf
• File Type:
  [PDF - 1.44 MB ]