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Biosynthesis of Fungal Indole Alkaloids
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10 2014
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Source: Nat Prod Rep. 31(10):1474-1487
[PDF-1.44 MB]
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Alternative Title:Nat Prod Rep
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Description:This review provides a summary of recent research advances in elucidating the biosynthesis of fungal indole alkaloids. The different strategies used to incorporate and derivatize the indole/indoline moieties in various families of fungal indole alkaloids will be discussed, including tryptophan-containing nonribosomal peptides, polyketide-nonribosomal peptide hybrids, and alkaloids derived from other indole building blocks. This review also includes a discussion regarding the downstream modifications that generate chemical and structural diversity among indole alkaloids.
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Pubmed ID:25180619
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Pubmed Central ID:PMC4162825
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Volume:31
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Issue:10
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