Biosynthesis of Fungal Indole Alkaloids

Xu, Wei; Gavia, Diego J.; Tang, Yi

doi:10.1039/c4np00073k

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Biosynthesis of Fungal Indole Alkaloids

10 2014
By Xu, Wei ; Gavia, Diego J. ; Tang, Yi
http://dx.doi.org/10.1039/c4np00073k
Source: Nat Prod Rep. 31(10):1474-1487

[PDF-1.44 MB]

English

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Details:

Alternative Title:

Nat Prod Rep
Personal Author:

Xu, Wei ; Gavia, Diego J. ; Tang, Yi

Xu, Wei ; Gavia, Diego J. ; Tang, Yi Less -
Description:

This review provides a summary of recent research advances in elucidating the biosynthesis of fungal indole alkaloids. The different strategies used to incorporate and derivatize the indole/indoline moieties in various families of fungal indole alkaloids will be discussed, including tryptophan-containing nonribosomal peptides, polyketide-nonribosomal peptide hybrids, and alkaloids derived from other indole building blocks. This review also includes a discussion regarding the downstream modifications that generate chemical and structural diversity among indole alkaloids.
Keywords:

[+]

Fungi Indole Alkaloids Molecular Structure
Source:

Nat Prod Rep. 31(10):1474-1487
Pubmed ID:

25180619
Pubmed Central ID:

PMC4162825
Document Type:

Journal Article
Funding:

DP1 GM106413/GM/NIGMS NIH HHSUnited States/ ; R56 AI101141/AI/NIAID NIH HHSUnited States/ ; 1DP1GM106413/DP/NCCDPHP CDC HHSUnited States/ ; 1R56AI101141/AI/NIAID NIH HHSUnited States/

DP1 GM106413/GM/NIGMS NIH HHSUnited States/ ; R56 AI101141/AI/NIAID NIH HHSUnited States/ ; 1DP1GM106413/DP/NCCDPHP CDC HHSUnited States/ ; 1R56AI101141/AI/NIAID NIH HHSUnited States/ Less -
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CDC Public Access
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urn:sha256:7786f909ce0b2d05460f344d5a51bf8cf9b7e75af1f89facd2f63fba98cf82f8
Download URL:

https://stacks.cdc.gov/view/cdc/30118/cdc_30118_DS1.pdf
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