Healthcare Worker Exposures to the Antibacterial Agent Triclosan

MacIsaac, Julia K.; Gerona, Roy; Blanc, Paul D.; Apatira, Latifat; Friesen, Matthew; Coppolino, Michael; Janssen, Sarah

doi:10.1097/JOM.0000000000000183

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Healthcare Worker Exposures to the Antibacterial Agent Triclosan

Published Date:

Aug 2014

Publisher's site:

http://dx.doi.org/10.1097/JOM.0000000000000183 New Site Icon

Source:

J Occup Environ Med. 56(8):834-839.

[PDF - 213.01 KB]

Details:

Personal Authors:

MacIsaac, Julia K. ; Gerona, Roy ; Blanc, Paul D. ; Apatira, Latifat ; Friesen, Matthew ; ... More ▼

Keywords:

[+]

Pubmed ID:

25099409

Pubmed Central ID:

PMC4133120

Description:

Objective

We sought to quantify absorption of triclosan, a potential endocrine disruptor, in healthcare workers with occupational exposure to soap containing this chemical.

Methods

A cross-sectional convenience sample of two groups of 38 healthcare workers at separate inpatient medical centers: Hospital One uses 0.3% triclosan soap in all patient care areas; Hospital Two does not use triclosan-containing products. Additional exposure to triclosan-containing personal care products was assessed through a structured questionnaire. Urine triclosan was quantified and the occupational contribution estimated through regression modeling.

Results

Occupational exposure accounted for an incremental triclosan burden of 206 ng/mL (p=0.02), while triclosan-containing toothpaste use was associated with 146 ng/mL higher levels (p<0.001).

Conclusions

Use of triclosan-containing antibacterial soaps in healthcare settings represents a substantial and potentially biologically relevant source occupational triclosan exposure.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

D33HP19037/PHS HHS/United States
T-42-OH008429/OH/NIOSH CDC HHS/United States
UL1 TR000004/TR/NCATS NIH HHS/United States
UL1 TR000004/TR/NCATS NIH HHS/United States

Supporting Files:

NIHMS580945-supplement-Laboratory_methods.docx	application/vnd.openxmlformats-officedocument.wordprocessingml.document
NIHMS580945-supplement-Supplemental_Digital_Content.docx	application/vnd.openxmlformats-officedocument.wordprocessingml.document
nihms580945.nxml	text/plain

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