Healthcare Worker Exposures to the Antibacterial Agent Triclosan

MacIsaac, Julia K.; Gerona, Roy; Blanc, Paul D.; Apatira, Latifat; Friesen, Matthew; Coppolino, Michael; Janssen, Sarah

doi:10.1097/JOM.0000000000000183

i

Healthcare Worker Exposures to the Antibacterial Agent Triclosan

Supporting Files

Aug 2014
By MacIsaac, Julia K. ; Gerona, Roy ; Blanc, Paul D. ; ...

Details

Alternative Title:

J Occup Environ Med
Personal Author:

MacIsaac, Julia K. ; Gerona, Roy ; Blanc, Paul D. ; Apatira, Latifat ; Friesen, Matthew ; Coppolino, Michael ; Janssen, Sarah
Description:

Objective

We sought to quantify absorption of triclosan, a potential endocrine disruptor, in healthcare workers with occupational exposure to soap containing this chemical.

Methods

A cross-sectional convenience sample of two groups of 38 healthcare workers at separate inpatient medical centers: Hospital One uses 0.3% triclosan soap in all patient care areas; Hospital Two does not use triclosan-containing products. Additional exposure to triclosan-containing personal care products was assessed through a structured questionnaire. Urine triclosan was quantified and the occupational contribution estimated through regression modeling.

Results

Occupational exposure accounted for an incremental triclosan burden of 206 ng/mL (p=0.02), while triclosan-containing toothpaste use was associated with 146 ng/mL higher levels (p<0.001).

Conclusions

Use of triclosan-containing antibacterial soaps in healthcare settings represents a substantial and potentially biologically relevant source occupational triclosan exposure.
Subjects:

Adult Anti-Infective Agents, Local Article Body Burden Female Humans Male Middle Aged Occupational Exposure Skin Absorption Soaps Toothpastes Triclosan
Source:

J Occup Environ Med. 56(8):834-839.
Pubmed ID:

25099409
Pubmed Central ID:

PMC4133120
Document Type:

Journal Article
Funding:

D33HP19037/PHS HHS/United States ; T-42-OH008429/OH/NIOSH CDC HHS/United States ; UL1 TR000004/TR/NCATS NIH HHS/United States
Volume:

56
Issue:

8
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:6f8d513ce766cd6bfd12958b32cb08e3155736b32827f2f2db819bdfe3d9dc2f
Download URL:

https://stacks.cdc.gov/view/cdc/30080/cdc_30080_DS1.pdf
File Type:

[PDF - 213.01 KB ]

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