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Factors associated with influenza vaccine receipt in community dwelling adults and their children
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    Factors associated with influenza vaccine receipt are well studied in healthcare personnel, pregnant women, and the elderly. There has been substantially less research in community dwelling adults and children, and none among entire households. Many studies determine vaccination status by self-report or behavioral intention, outcomes susceptible to misclassification. Given that vaccine is recommended for everyone over six months, re-evaluating these factors is warranted.


    The Household Influenza Vaccine Effectiveness (HIVE) study is a prospective cohort of households with children. In 2010-2011, 549 adults representing 312 households completed surveys evaluating knowledge, attitudes, and practices regarding influenza vaccination for themselves and their children. Using the health belief model (HBM) as a framework, we examined factors associated with documented seasonal influenza vaccine receipt using log-binomial regression models.


    In multivariate models, cues to action such as doctor recommendation, (RR 1.62, 95% CI:1.25-2.10), perceived benefits (RR 1.25, 95% CI:1.04-1.50), and perceived susceptibility (RR 1.21, 95% CI:1.03-1.42) were significantly associated with increased likelihood of vaccine receipt among adults while high perceived barriers were associated with decreased likelihood (RR 0.38, 95% CI:0.25-0.59). Similarly, parents reporting higher barriers were less likely (RR 0.58, 95% CI:0.42-0.79) and those perceiving greater benefits (RR 4.16, 95% CI:2.28-7.59) and severity (RR 1.13, 95% CI:1.00-1.27 were more likely to vaccinate their children. The observed effects of perceptions of susceptibility, severity, and benefits were more pronounced at low cues to action for children, as were the effects of perceptions of barriers and severity among adults.


    Perceived benefits and barriers are most strongly associated with vaccine receipt. However, the effects of various factors were most pronounced in the absence of cues to action, which may be an important component of targeted interventions.

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    R01 AI097150/AI/NIAID NIH HHS/United States
    U01 IP000170/IP/NCIRD CDC HHS/United States
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