Inverse association between toenail arsenic and body mass index in a population of welders

Details

• Alternative Title:
  Environ Res
• Personal Author:
  Grashow, Rachel ; Zhang, Jinming ; Fang, Shona C. ; Weisskopf, Marc G. ; Christiani, David C. ; Kile, Molly L. ; Cavallari, Jennifer M.
• Description:
  Recent data show that arsenic may play a role in obesity-related diseases. However, urinary arsenic studies report an inverse association between arsenic level and body mass index (BMI). We explored whether toenail arsenic, a long-term exposure measure, was associated with BMI in 74 welders with known arsenic exposure. BMI showed significant inverse associations with toenail arsenic (p=0.01), which persisted in models adjusted for demographics, diet and work history. It is unclear whether low arsenic biomarker concentrations in high BMI subjects truly reflect lower exposures, or instead reflect internal or metabolic changes that alter arsenic metabolism and tissue deposition.
• Subjects:
  Adult Arsenic Article BMI Body Mass Index Environmental Health Humans Male Metals Nails Occupational Exposure Occupational Health Toenail Welding Welding Fume

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• Source:
  Environ Res. 2014; 131:131-133.
• Pubmed ID:
  24721130
• Pubmed Central ID:
  PMC4035809
• Document Type:
  Journal Article
• Funding:
  ES00002/ES/NIEHS NIH HHS/United States ; ES009860/ES/NIEHS NIH HHS/United States ; K01 ES017800/ES/NIEHS NIH HHS/United States ; K01 ES017800/ES/NIEHS NIH HHS/United States ; OH009762/OH/NIOSH CDC HHS/United States ; P30 ES000002/ES/NIEHS NIH HHS/United States ; R01 ES009860/ES/NIEHS NIH HHS/United States ; T32 ES007069/ES/NIEHS NIH HHS/United States ; T32ES7069/ES/NIEHS NIH HHS/United States
• Volume:
  131
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:8827b3167809b1152e25a0f4a05fdeb95c261eae3991693d0d5cc161e0619510
• Download URL:
  https://stacks.cdc.gov/view/cdc/29972/cdc_29972_DS1.pdf
• File Type:
  [PDF - 137.78 KB ]