Spatially Fourier-encoded photoacoustic microscopy using a digital micromirror device

Details

• Alternative Title:
  Opt Lett
• Personal Author:
  Liang, Jinyang ; Gao, Liang ; Li, Chiye ; Wang, Lihong V.
• Description:
  We have developed spatially Fourier-encoded photoacoustic (PA) microscopy using a digital micromirror device. The spatial intensity distribution of laser pulses is Fourier-encoded, and a series of such encoded PA measurements allows one to decode the spatial distribution of optical absorption. The throughput and Fellgett advantages were demonstrated by imaging a chromium target. By using 63 spatial elements, the signal-to-noise ratio in the recovered PA signal was enhanced by ∼4×. The system was used to image two biological targets, a monolayer of red blood cells and melanoma cells.
• Subjects:
  Absorption Animals Article Cattle Erythrocytes Fourier Analysis Melanoma, Experimental Microscopy Microtechnology Photoacoustic Techniques Signal-To-Noise Ratio

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• Source:
  Opt Lett. 2013; 39(3):430-433.
• Pubmed ID:
  24487832
• Pubmed Central ID:
  PMC3978131
• Document Type:
  Journal Article
• Funding:
  R01 CA134539/CA/NCI NIH HHS/United States ; R01CA134539/CA/NCI NIH HHS/United States ; R01CA157277/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; DP1 EB016986/EB/NIBIB NIH HHS/United States ; DP1 EB016986/DP/NCCDPHP CDC HHS/United States
• Volume:
  39
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:9d8f8d2288c63cc58dcc73e7d78c807c26c052908f12960c878efe72706c439b
• Download URL:
  https://stacks.cdc.gov/view/cdc/29910/cdc_29910_DS1.pdf
• File Type:
  [PDF - 1.95 MB ]