Welcome to CDC Stacks | Understanding Engineered Nanomaterial Skin Interactions and the Modulatory Effects of UVR Skin Exposure - 29809 | CDC Public Access
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
Understanding Engineered Nanomaterial Skin Interactions and the Modulatory Effects of UVR Skin Exposure
Filetype[PDF - 2.00 MB]


Details:
  • Pubmed ID:
    24123977
  • Pubmed Central ID:
    PMC3865219
  • Description:
    The study of engineered nanomaterials for the development of technological applications, nanomedicine, and nano-enabled consumer products is an ever-expanding discipline as is the concern over the impact of nanotechnology on human environmental health and safety. In this review, we discuss the current state of understanding of nanomaterial skin interactions with a specific emphasis on the effects of ultraviolet radiation (UVR) skin exposure. Skin is the largest organ of the body and is typically exposed to UVR on a daily basis. This necessitates the need to understand how UVR skin exposure can influence nanomaterial skin penetration, alter nanomaterial systemic trafficking, toxicity, and skin immune function. We explore the unique dichotomy that UVR has on inducing both deleterious and therapeutic effects in skin. The subject matter covered in this review is broadly informative and will raise awareness of potential increased risks from nanomaterial skin exposure associated with specific occupational and life style choices. The UVR-induced immunosuppressive response in skin raises intriguing questions that motivate future research directions in the nanotoxicology and nanomedicine fields.

  • Document Type:
  • Collection(s):
  • Funding:
    OH009970/OH/NIOSH CDC HHS/United States
    R01 ES021492/ES/NIEHS NIH HHS/United States
    R01 ES021492/ES/NIEHS NIH HHS/United States
No Related Documents.
You May Also Like: