Details:

Alternative Title:
Opt Lett
Personal Author:
Zhou, Yong ; Liang, Jinyang ; Maslov, Konstantin I. ; Wang, Lihong V.
Zhou, Yong ; Liang, Jinyang ; Maslov, Konstantin I. ; Wang, Lihong V. Less -
Description:
We propose a cross-correlation-based method to measure blood-flow velocity by using photoacoustic microscopy. Unlike in previous autocorrelation-based methods, the measured flow velocity here is independent of particle size. Thus an absolute flow velocity can be obtained without calibration. We first measured the flow velocity ex vivo, using defibrinated bovine blood. Then flow velocities in vessels with different structures in a mouse ear were quantified in vivo. We further measured the flow variation in the same vessel and at a vessel bifurcation. All the experimental results indicate that our method can be used to accurately quantify blood velocity in vivo.
Subject:
[+]
Animals
Article
Blood Flow Velocity
Calibration
Cattle
Hemodynamics
Hemorheology
Mice
Microscopy
Photoacoustic Techniques
Time Factors

Source:
Opt Lett. 2013; 38(19):3882-3885.
Pubmed ID:
24081077
Pubmed Central ID:
PMC3831365
Document Type:
Journal Article
Funding:
T32 EB014855/EB/NIBIB NIH HHS/United States ; R01 CA134539/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; U54 CA136398/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; ... More +
T32 EB014855/EB/NIBIB NIH HHS/United States ; R01 CA134539/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; U54 CA136398/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; R01 EB010049/EB/NIBIB NIH HHS/United States ; DP1 EB016986/EB/NIBIB NIH HHS/United States ; R01 EB008085/EB/NIBIB NIH HHS/United States ; DP1 EB016986/DP/NCCDPHP CDC HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:c966a972c841d8fdc5f8b66ae0d99850a35f3e0853330176e4d3054e07590259
File Type:

Supporting Files

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