Details:

Alternative Title:
Opt Lett
Personal Author:
Liang, Jinyang ; Zhou, Yong ; Winkler, Amy W. ; Wang, Lidai ; Maslov, Konstantin I. ; ... More +
Liang, Jinyang ; Zhou, Yong ; Winkler, Amy W. ; Wang, Lidai ; Maslov, Konstantin I. ; Li, Chiye ; Wang, Lihong V. ; Less -
Description:
We developed random-access optical-resolution photoacoustic microscopy using a digital micromirror device. This system can rapidly scan arbitrarily shaped regions of interest within a 40 μm×40 μm imaging area with a lateral resolution of 3.6 μm. To identify a region of interest, a global structural image is first acquired, then the selected region is scanned. The random-access ability was demonstrated by imaging two static samples, a carbon fiber cross and a monolayer of red blood cells, with an acquisition rate up to 4 kHz. The system was then used to monitor blood flow in vivo in real time within user-selected capillaries in a mouse ear. By imaging only the capillary of interest, the frame rate was increased by up to 9.2 times.
Subject:
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Animals
Article
Ear
Mice
Microscopy
Optical Devices
Photoacoustic Techniques

Source:
Opt Lett. 2013 ; 38(15):2683-2686.;
Pubmed ID:
23903111
Pubmed Central ID:
PMC3784350
Document Type:
Journal Article ;
Funding:
T32 EB014855/EB/NIBIB NIH HHS/United States ; R01 CA134539/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; U54 CA136398/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; ... More +
T32 EB014855/EB/NIBIB NIH HHS/United States ; R01 CA134539/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; U54 CA136398/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; R01 EB010049/EB/NIBIB NIH HHS/United States ; DP1 EB016986/EB/NIBIB NIH HHS/United States ; R01 EB008085/EB/NIBIB NIH HHS/United States ; DP1 EB016986/DP/NCCDPHP CDC HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f5f785ff64e74ac11b514c92865511e8daeb539fa47d819475b30b384dda4f8f
File Type:

Supporting Files

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