Details:

Alternative Title:
J Biophotonics
Publisher's site:
http://dx.doi.org/10.1002/jbio.201400055
Personal Author:
Yeh, Chenghung ; Soetikno, Brian ; Hu, Song ; Maslov, Konstantin I. ; Wang, Lihong V.
Yeh, Chenghung ; Soetikno, Brian ; Hu, Song ; Maslov, Konstantin I. ; Wang, Lihong V. Less -
Description:
We have enhanced photoacoustic microscopy with three-dimensional arbitrary trajectory (3-DAT) scanning, which can rapidly image selected vessels over a large field of view (FOV) and maintain a high signal-to-noise ratio (SNR) despite the depth variation of the vessels. We showed that hemoglobin oxygen saturation (sO2 ) and blood flow can be measured simultaneously in a mouse ear in vivo at a frame rate 67 times greater than that of a traditional two-dimensional raster scan. We also observed sO2 dynamics in response to switching from systemic hypoxia to hyperoxia. 3-DAT-scanning photoacoustic microscopy. Schematic diagram of the 3D scanning stage and method.
Subject:
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3-D Arbitrary Trajectory Scanning
Article
Hemoglobin Oxygen Saturation
Metabolic Rate Of Oxygen
Optical-resolution Photoacoustic Microscopy
Raster Scanning

Source:
J Biophotonics. 2014; 8(4):303-308.
Document Type:
Journal Article
Funding:
DP1 EB016986/DP/NCCDPHP CDC HHS/United States ; DP1 EB016986/EB/NIBIB NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; R01 CA186567/CA/NCI NIH HHS/United States ; ... More +
DP1 EB016986/DP/NCCDPHP CDC HHS/United States ; DP1 EB016986/EB/NIBIB NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; R01 CA186567/CA/NCI NIH HHS/United States ; R01 CA186567/CA/NCI NIH HHS/United States ; R01 EB016963/EB/NIBIB NIH HHS/United States ; R01 EB016963/EB/NIBIB NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:e64a763898bb7303fcf5cbaf0341897923e49566b13ea24b18e8d81cd459480e
File Type:

Supporting Files

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