The Association between Obstructive Sleep Apnea and Hypertension by Race/Ethnicity in a Nationally Representative Sample
Published Date:Jun 10 2013
Source:J Clin Hypertens (Greenwich). 15(8):593-599.
African Continental Ancestry Group
Body Mass Index
European Continental Ancestry Group
Sleep Apnea, Obstructive
Sleep Problems And Hypertension
Pubmed Central ID:PMC3733493
Funding:K23 HL110216/HL/NHLBI NIH HHS/United States
K23HL110216/HL/NHLBI NIH HHS/United States
R01-OH009149/OH/NIOSH CDC HHS/United States
R21 ES022931/ES/NIEHS NIH HHS/United States
R21ES022931/ES/NIEHS NIH HHS/United States
T32HL07713-19/HL/NHLBI NIH HHS/United States
UL1RR024134/RR/NCRR NIH HHS/United States
The association between OSA and hypertension by race/ethnicity has not been well characterized in a national sample.
Adult participants in the 2007–2008 National Health and Nutrition Examination Survey.
We reviewed self-reports of sleep apnea diagnosis, snorting, gasping or stopping breathing during sleep and snoring to derive whether OSA was probable (pOSA). Multivariable logistic regression determined whether pOSA predicted hypertension in the cohort, and BMI and ethno-racial strata.
pOSA predicted hypertension in several groups: 1) Within BMI strata, there was a significant association among overweight individuals [OR (95% CI) =1.82 (1.26–2.62)]; 2) In race/ethnicity subgroups, the association was significant among Hispanic/Latinos [OR (95% CI) =1.69 (1.13, 2.53)] and whites [OR (95% CI) =1.40 (1.07, 1.84)]; 3) In models stratified by both race/ethnicity and weight, pOSA predicted hypertension among overweight Black/African Americans [OR (95% CI) =4.74 (1.86–12.03)], overweight whites [OR (95% CI) =1.65 (1.06, 2.57)], and obese Hispanic/Latino participants [OR (95% CI) =2.01 (1.16, 3.49)].
A simple, self-report tool for OSA was strongly associated with hypertension, and may serve as a potential future opportunity for OSA diagnosis.
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