Highly Pathogenic Avian Influenza A(H5N1) Virus Infection among Workers at Live Bird Markets, Bangladesh, 2009–2010

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nasreen, Sharifa ; Khan, Salah Uddin ; Luby, Stephen P. ; Gurley, Emily S. ; Abedin, Jaynal ; Zaman, Rashid Uz ; Sohel, Badrul Munir ; Rahman, Mustafizur ; Hancock, Kathy ; Levine, Min Z. ; Veguilla, Vic ; Wang, David ; Holiday, Crystal ; Gillis, Eric ; Sturm-Ramirez, Katharine ; Bresee, Joseph S. ; Rahman, Mahmudur ; Uyeki, Timothy M. ; Katz, Jacqueline M. ; Azziz-Baumgartner, Eduardo
• Description:
  The risk for influenza A(H5N1) virus infection is unclear among poultry workers in countries where the virus is endemic. To assess H5N1 seroprevalence and seroconversion among workers at live bird markets (LBMs) in Bangladesh, we followed a cohort of workers from 12 LBMs with existing avian influenza surveillance. Serum samples from workers were tested for H5N1 antibodies at the end of the study or when LBM samples first had H5N1 virus-positive test results. Of 404 workers, 9 (2%) were seropositive at baseline. Of 284 workers who completed the study and were seronegative at baseline, 6 (2%) seroconverted (7 cases/100 poultry worker-years). Workers who frequently fed poultry, cleaned feces from pens, cleaned food/water containers, and did not wash hands after touching sick poultry had a 7.6 times higher risk for infection compared with workers who infrequently performed these behaviors. Despite frequent exposure to H5N1 virus, LBM workers showed evidence of only sporadic infection.
• Subjects:
  Adolescent Adult Farmers Female History, 21st Century Humans Incidence Influenza, Human/epidemiology Influenza, Human/history Influenza, Human/transmission Influenza, Human/virology Influenza A Virus, H5N1 Subtype Male Middle Aged Population Surveillance Research Risk Factors Seroepidemiologic Studies Serotyping Young Adult

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• Source:
  Emerg Infect Dis. 21(4):629-637.
• Document Type:
  Journal Article
• Place as Subject:
  Bangladesh
• Location:
  Asia
• Volume:
  21
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:caa1ca981ed87e6157b8a794c20c00dc64dffc12f8f04b5834e08e426c6ec620
• Download URL:
  https://stacks.cdc.gov/view/cdc/29298/cdc_29298_DS1.pdf
• File Type:
  [PDF - 1.81 MB ]