Deaths Associated with Respiratory Syncytial and Influenza Viruses among Persons ≥5 Years of Age in HIV-Prevalent Area, South Africa, 1998–2009

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Tempia, Stefano ; Walaza, Sibongile ; Viboud, Cecile ; Cohen, Adam L. ; Madhi, Shabir A. ; Venter, Marietjie ; von Mollendorf, Claire ; Moyes, Jocelyn ; McAnerney, Johanna M. ; Cohen, Cheryl
• Description:
  We estimated deaths attributable to influenza and respiratory syncytial virus (RSV) among persons >5 years of age in South Africa during 1998-2009 by applying regression models to monthly deaths and laboratory surveillance data. Rates were expressed per 100,000 person-years. The mean annual number of seasonal influenza-associated deaths was 9,093 (rate 21.6). Persons >65 years of age and HIV-positive persons accounted for 50% (n = 4,552) and 28% (n = 2,564) of overall seasonal influenza-associated deaths, respectively. In 2009, we estimated 4,113 (rate 9.2) influenza A(H1N1)pdm09-associated deaths. The mean of annual RSV-associated deaths during the study period was 511 (rate 1.2); no RSV-associated deaths were estimated in persons >45 years of age. Our findings support the recommendation for influenza vaccination of older persons and HIV-positive persons. Surveillance for RSV should be strengthened to clarify the public health implications and severity of illness associated with RSV infection in South Africa.
• Subjects:
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 And Over
  • Child
  • Child, Preschool
  • Coinfection
  • Female
  • Hiv Infections/Epidemiology
  More +
• Source:
  Emerg Infect Dis. 21(4):600-608.
• Document Type:
  Journal Article
• Genre:
  Historical Article
• Place as Subject:
  South Africa
• Volume:
  21
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/29296/cdc_29296_DS1.pdf
• File Type:
  [PDF - 1.14 MB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b25bf2a354bb815fa40b64129a33f1d8fdb8368812da2d4242ffd940a4f772a9