Details:

Alternative Title:
Diabetes Care
Personal Author:
Marcinkevage, Jessica A. ; Alverson, C.J. ; Narayan, K.M. Venkat ; Kahn, Henry S. ; Ruben, Julia ; ... More +
Marcinkevage, Jessica A. ; Alverson, C.J. ; Narayan, K.M. Venkat ; Kahn, Henry S. ; Ruben, Julia ; Correa, Adolfo Less -
Description:
OBJECTIVE

To describe the burden of dysglycemia—abnormal glucose metabolism indicative of diabetes or high risk for diabetes—among U.S. women of childbearing age, focusing on differences by race/ethnicity.

RESEARCH DESIGN AND METHODS

Using U.S. National Health and Nutrition Examination Survey data (1999–2008), we calculated the burden of dysglycemia (i.e., prediabetes or diabetes from measures of fasting glucose, A1C, and self-report) in nonpregnant women of childbearing age (15–49 years) by race/ethnicity status. We estimated prevalence risk ratios (PRRs) for dysglycemia in subpopulations stratified by BMI (measured as kilograms divided by the square of height in meters), using predicted marginal estimates and adjusting for age, waist circumference, C-reactive protein, and socioeconomic factors.

RESULTS

Based on data from 7,162 nonpregnant women, representing >59,000,000 women nationwide, 19% (95% CI 17.2–20.9) had some level of dysglycemia, with higher crude prevalence among non-Hispanic blacks and Mexican Americans vs. non-Hispanic whites (26.3% [95% CI 22.3–30.8] and 23.8% [19.5–28.7] vs. 16.8% [14.4–19.6], respectively). In women with BMI <25 kg/m2, dysglycemia prevalence was roughly twice as high in both non-Hispanic blacks and Mexican Americans vs. non-Hispanic whites. This relative increase persisted in adjusted models (PRRadj 1.86 [1.16–2.98] and 2.23 [1.38–3.60] for non-Hispanic blacks and Mexican Americans, respectively). For women with BMI 25–29.99 kg/m2, only non-Hispanic blacks showed increased prevalence vs. non-Hispanic whites (PRRadj 1.55 [1.03–2.34] and 1.28 [0.73–2.26] for non-Hispanic blacks and Mexican Americans, respectively). In women with BMI >30 kg/m2, there was no significant increase in prevalence of dysglycemia by race/ethnicity category.

CONCLUSIONS

Our findings show that dysglycemia affects a significant portion of U.S. women of childbearing age and that disparities by race/ethnicity are most prominent in the nonoverweight/nonobese.


Subject:
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Adolescent Adult African Americans Age Factors Blacks Blood Glucose Body Weight C-Reactive Protein Diabetes Mellitus Female Hispanic Americans Humans Middle Aged Prediabetic State Socioeconomic Factors Waist Circumference Whites Young Adult
Source:
Diabetes Care. 2013; 36(10):3033-3039.
Document Type:
Journal Article
Funding:
T32 DK007734/DK/NIDDK NIH HHS/United States
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f5cb9c800299e951f0a6d11f754e17cb2274b871569fbba139695bf127e321c8
Download URL:
https://stacks.cdc.gov/view/cdc/29292/cdc_29292_DS1.pdf
File Type:

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