Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand

Garg, Shikha; Olsen, Sonja J.; Fernandez, Stefan; Muangchana, Charung; Rungrojcharoenkit, Kamonthip; Prapasiri, Prabda; Katz, Jacqueline M.; Curlin, Marcel E.; Gibbons, Robert V.; Holtz, Timothy H.; Chitwarakorn, Anupong; Dawood, Fatimah S.

doi:10.1093/ofid/ofu082

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Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand

Published Date:

Oct 10 2014

Publisher's site:

http://dx.doi.org/10.1093/ofid/ofu082

Source:

Open Forum Infect Dis. 2014; 1(3).

[PDF-357.85 KB]

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Open Forum Infect Dis

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Garg, Shikha ; Olsen, Sonja J. ; Fernandez, Stefan ; Muangchana, Charung ; Rungrojcharoenkit, Kamonthip ; ... More ▼

Description:

Among 368 Thai men who have sex with men with paired serum samples collected before and during the 2009 H1N1 influenza pandemic, we determined influenza A (H1N1)pdm09 seroconversion rates (≥4-fold rise in antibody titers by hemagglutination inhibition or microneutralization assays). Overall, 66 of 232 (28%) participants seroconverted after the first year of A(H1N1)pdm09 activity, and 83 of 234 (35%) participants seroconverted after the second year. Influenza A(H1N1)pdm09 seroconversion did not differ between human immunodeficiency virus (HIV)-infected (55 of 2157 [35%]) and HIV-uninfected (71 of 2211 [34%]) participants (P = .78). Influenza A(H1N1)pdm09 seroconversion occurred in approximately one third of our Thai study population and was similar among HIV-infected and HIV-uninfected participants.

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