Serotypes, seasonal trends, and antibiotic resistance of non-typhoidal Salmonella from human patients in Guangdong Province, China, 2009–2012

Details

• Alternative Title:
  BMC Infect Dis
• Personal Author:
  Liang, Zhaoming ; Ke, Bixia ; Deng, Xiaoling ; Liang, Junhua ; Ran, Lu ; Lu, Lingling ; He, Dongmei ; Huang, Qiong ; Ke, Changwen ; Li, Zhongjie ; Yu, Hongjie ; Klena, John D ; Wu, Shuyu
• Description:
  Background
  
  Non-typhoidal Salmonella is a common cause of infectious diarrhea in humans. Antimicrobial-resistant Salmonella has become a global concern.
  
  Methods
  
  Using laboratory-based surveillance system for Salmonella from September 2009 to December 2012 in Guangdong Province of China. The clinical information and samples of diarrhea patients were collected, according to the surveillance case definition. The lab tests were followed by standardized protocols, including sample isolation, isolates confirmation, serotyping, and antimicrobial susceptibility testing (AST).
  
  Results
  
  A total of 1,826 Salmonella isolates were identified from40,572 patients in 28 hospitals in11 prefectures. The isolates ratio was highest in autumn (38.8%, 708/1826) and lowest in winter (6.4%, 117/1826). Children aged <5 years were the group most affected by Salmonella in Guangdong Province accounting for 73% (1,329/1,826), of whom the infants (<1 year) were 81.5% (1084/1329) especially. A total of 108 serotypes were identified among the isolates. S. Typhimurium represented the most common serotype followed by serotype 4,5,12:i:-.
  
  Conclusions
  
  Additional data and more refined methods can improve future surveillance. The invasive Salmonella isolates should also be included to the antibiotic resistance surveillance for clinical care or public health.
  
  
• Subjects:
  Research Article
• Source:
  BMC Infect Dis. 15.
• Document Type:
  Journal Article
• Volume:
  15
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:11b5d42e123419f5de4efc77c1ae4e82880ddf8e33c90914b731c38f870d78e0
• Download URL:
  https://stacks.cdc.gov/view/cdc/28173/cdc_28173_DS1.pdf
• File Type:
  [PDF - 810.37 KB ]