Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups

Malogolovkin, Alexander; Burmakina, Galina; Titov, Ilya; Sereda, Alexey; Gogin, Andrey; Baryshnikova, Elena; Kolbasov, Denis

doi:10.3201/eid2102.140649

i

Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups

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Feb 2015
By Malogolovkin, Alexander ; Burmakina, Galina ; Titov, Ilya ; ...

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Emerg Infect Dis
Personal Author:

Malogolovkin, Alexander ; Burmakina, Galina ; Titov, Ilya ; Sereda, Alexey ; Gogin, Andrey ; Baryshnikova, Elena ; Kolbasov, Denis
Description:

African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.
Subjects:

African Swine Fever African Swine Fever Virus Animals Genes, Viral Genotype Geography, Medical Global Health Phylogeny Serogroup Swine
Source:

Emerg Infect Dis. 21(2):312-315.
Document Type:

Journal Article
Volume:

21
Issue:

2
Collection(s):

Emerging Infectious Diseases
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urn:sha256:1223cb63b64d5e33f91b77a73a32ddd2f28cf044c5f04762ef8d05baac326cc9
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https://stacks.cdc.gov/view/cdc/27421/cdc_27421_DS1.pdf
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