Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups

Malogolovkin, Alexander; Burmakina, Galina; Titov, Ilya; Sereda, Alexey; Gogin, Andrey; Baryshnikova, Elena; Kolbasov, Denis

doi:10.3201/eid2102.140649

i

Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups

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Alternative Title:

Emerg Infect Dis
Personal Author:

Malogolovkin, Alexander ; Burmakina, Galina ; Titov, Ilya ; Sereda, Alexey ; Gogin, Andrey ; Baryshnikova, Elena ; Kolbasov, Denis
Description:

African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.
Subjects:
Source:

Emerg Infect Dis. 21(2):312-315.
Document Type:

Journal Article
Volume:

21
Issue:

2
Download URL:

https://stacks.cdc.gov/view/cdc/27421/cdc_27421_DS1.pdf
File Type:

[PDF - 362.42 KB]
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:1223cb63b64d5e33f91b77a73a32ddd2f28cf044c5f04762ef8d05baac326cc9

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