Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2102.140649
Personal Author:
Malogolovkin, Alexander ; Burmakina, Galina ; Titov, Ilya ; Sereda, Alexey ; Gogin, Andrey ; ... More +
Malogolovkin, Alexander ; Burmakina, Galina ; Titov, Ilya ; Sereda, Alexey ; Gogin, Andrey ; Baryshnikova, Elena ; Kolbasov, Denis Less -
Description:
African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.
Subject:
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African Swine Fever Virus
Antigenic Diversity
Comparative Analysis Of African Swine Fever Virus Genotypes And Serogroups
Cross-protective Responses
Dispatch
Domestic Pigs
Genotypes
Hemadsorption Inhibition Assay
Phylogenetic Analysis
Serogroups
Swine
Vaccine Development
Viruses

Source:
Emerg Infect Dis. 21(2):312-315.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:1223cb63b64d5e33f91b77a73a32ddd2f28cf044c5f04762ef8d05baac326cc9
File Type:

Supporting Files

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