Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Gayet-Ageron, Angèle ; Sednaoui, Patrice ; Lautenschlager, Stephan ; Ferry, Tristan ; Toutous-Trellu, Laurence ; Cavassini, Matthias ; Yassir, Fatima ; Martinez de Tejada, Begoña ; Emonet, Stéphane ; Combescure, Christophe ; Schrenzel, Jacques ; Perneger, Thomas
• Description:
  Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.
• Subjects:
  Bacteria Dispatch France Pcr Sensitivity Sexually Transmitted Infections Specificity Switzerland Syphilis Tp47 Protein Treponema Pallidum Ulcers Use Of Treponema Pallidum Pcr In Testing Of Ulcers For Diagnosis Of Primary Syphilis

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• Source:
  Emerg Infect Dis. 21(1):127-129.
• Document Type:
  Journal Article
• Volume:
  21
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:26890eec08ab13b8490b5cde20e56e69f1941ecea4181c142d20ab467e44bb21
• Download URL:
  https://stacks.cdc.gov/view/cdc/26678/cdc_26678_DS1.pdf
• File Type:
  [PDF - 359.88 KB ]