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Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
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  1. Failure of PCR to Detect Treponema pallidum ssp. pertenue DNA in Blood in Latent Yaws
    Personal Author:
    Marks, Michael; Katz, Samantha; Chi, Kai-Hua; Vahi, Ventis; Sun, Yongcheng; Mabey, David C.; Solomon, Anthony W.; Chen, Cheng Y.; Pillay, Allan;
    Published Date:
    Jun 30 2015
    Source:
    PLoS Negl Trop Dis. 9(6).
    Description:
    Yaws, caused by Treponema pallidum ssp. pertenue, is a neglected tropical disease closely related to venereal syphilis and is targeted for eradication by 2020. Latent yaws represents a diagnostic challenge, and current tools cannot adequately disting...
    File Type:
    Filetype[PDF - 190.22 KB]
  2. Screening for sexually transmitted diseases during the domestic medical examination for newly arrived refugees
    Corporate Authors:
    National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Global Migration and Quarantine.
    Published Date:
    April 7, 2014
    Description:
    Sexually transmitted diseases (STDs) are a major cause of acute illness and infertility worldwide. The World Health Organization (WHO) estimates that 499 million new cases of curable STDs occur annually worldwide in adults aged 1549 years . The la...
    Status:
    superseded
    File Type:
    Filetype[PDF - 286.80 KB]
  3. Multiplex Mediator Displacement Loop-Mediated Isothermal Amplification for Detection of Treponema pallidum and Haemophilus ducreyi
    Personal Author:
    Becherer, Lisa; Knauf, Sascha; Marks, Michael; Lueert, Simone; Frischmann, Sieghard; Borst, Nadine; von Stetten, Felix; Bieb, Sibauk; Adu-Sarkodie, Yaw; Asiedu, Kingsley; Mitjà, Oriol; Bakheit, Mohammed;
    Published Date:
    Feb 2020
    Source:
    Emerg Infect Dis. 26(2):282-288
    Description:
    Yaws, a neglected tropical disease caused by the bacterium Treponema pallidum subspecies pertenue, manifests as ulcerative skin lesions. Nucleic acid amplification tests, like loop-mediated isothermal amplification (LAMP), are versatile tools to dist...
    File Type:
    Filetype[PDF - 1.80 MB]
  4. Correlates of Bacterial Ulcers and Acute HSV-2 Infection among Men with Genital Ulcer Disease in South Africa: Age, Recent Sexual Behaviors, and HIV
    Personal Author:
    Leichliter, Jami S.; Lewis, David A.; Paz-Bailey, Gabriela;
    Published Date:
    Jan 25 2016
    Source:
    S Afr J Infect Dis. 31(2):61-65.
    Description:
    Data from baseline surveys and STI/HIV laboratory tests (n=615 men) were used to examine correlates of bacterial ulcers (Treponema pallidum, Haemophilus ducreyi, or Chlamydia trachomatis L1-L3 detected in ulcer) and acute HSV-2 ulcers (HSV-2 positive...
    File Type:
    Filetype[PDF - 71.45 KB]
  5. Screening for sexually transmitted diseases during the domestic medical examination for newly arrived refugees
    Corporate Authors:
    National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Global Migration and Quarantine.
    Published Date:
    April 16, 2012
    Description:
    Sexually transmitted infections (STIs) are a major cause of acute illness and infertility worldwide. The World Health Organization (WHO) estimates that 448 million new cases of curable STIs occur annually worldwide in adults aged 15-49 years. The lar...
    Status:
    superseded
    File Type:
    Filetype[PDF - 285.12 KB]