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Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
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  1. Failure of PCR to Detect Treponema pallidum ssp. pertenue DNA in Blood in Latent Yaws
    Personal Author:
    Marks, Michael; Katz, Samantha; Chi, Kai-Hua; Vahi, Ventis; Sun, Yongcheng; Mabey, David C.; Solomon, Anthony W.; Chen, Cheng Y.; Pillay, Allan;
    Published:
    Jun 30 2015
    Source:
    PLoS Negl Trop Dis. 9(6).
    Description:
    Yaws, caused by Treponema pallidum ssp. pertenue, is a neglected tropical disease closely related to venereal syphilis and is targeted for eradication by 2020. Latent yaws represents a diagnostic challenge, and current tools cannot adequately disting...
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  2. Testing umbilical cords for funisitis due to Treponema pallidum infection, Bolivia.
    Personal Author:
    Guarner, J.; Southwick, K.; Greer, P.; Bartlett, J.; Santander, A.; Blanco, S.; Pope, V.; Levine, W.; Zaki, S.;
    Published:
    2000 Sep-Oct
    Source:
    Emerg Infect Dis. 6(5):487-492.
    Description:
    To establish the frequency of necrotizing funisitis in congenital syphilis, we conducted a prospective descriptive study of maternal syphilis in Bolivia by testing 1,559 women at delivery with rapid plasma reagin (RPR). We examined umbilical cords of...
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  3. The Tprk Protein of Treponema pallidum Is Periplasmic and Is Not a Target of Opsonic Antibody or Protective Immunity
    Personal Author:
    Hazlett, Karsten R.O.; Sellati, Timothy J.; Nguyen, Tung T.; Cox, David L.; Clawson, Michael L.; Caimano, Melissa J.; Radolf, Justin D.;
    Published:
    May 7 2001
    Source:
    J Exp Med. 2001; 193(9):1015-1026.
    Description:
    The finding that Treponema pallidum, the syphilis spirochete, contains 12 orthologs of the Treponema denticola outer membrane major sheath protein has engendered speculation that members of this T. pallidum repeat (Tpr) family may be similarly surfac...
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  4. Optimizing Infant HIV Diagnosis in Resource-Limited Settings: Modeling the Impact of HIV DNA PCR Testing at Birth
    Personal Author:
    Chiu, Alexander; Modi, Surbhi; Rivadeneira, Emilia D.; Koumans, Emilia H.;
    Published:
    Dec 01 2016
    Source:
    J Acquir Immune Defic Syndr. 73(4):454-462.
    Description:
    Background : Early antiretroviral therapy (ART) initiation in HIV-infected infants significantly improves survival but is often delayed in resource-limited settings. Adding HIV testing of infants at birth to the current recommendation of testing at a...
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  5. Real-Time PCR for Diagnosis of Oculoglandular Tularemia
    Personal Author:
    Maurin, Max; Castan, Bernard; Roch, Nathalie; Gestin, Brieuc; Pelloux, Isabelle; Mailles, Alexandra; Chiquet, Christophe; Chavanet, Pascal;
    Published:
    Jan 2010
    Source:
    Emerg Infect Dis. 16(1):152-153.
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