Risk Factors and Clinical Correlates of Sensory Dysfunction in Preschool Children With and Without Autism Spectrum Disorder.

Details

• Alternative Title:
  Autism Research : Official Journal of the International Society for Autism Research, 2024, v. 17, no. 1: Risk Factors and Clinical Correlates of Sensory Dysfunction in Preschool Children With and Without Autism Spectrum Disorder.
• Journal Article:
  Autism Research : Official Journal of the International Society for Autism Research
• Personal Author:
  Wiggins, Lisa D. ; Overwyk, Katie ; Daniels, Julie ; Barger, Brian ; Crain, Hayley ; Grzadzinski, Rebecca ; Moody, Eric ; Reynolds, Ann ; Reyes, Nuri ; Rosenberg, Cordelia ; Rosenberg, Steven ; Pazol, Karen
• Description:
  Sensory dysfunction is a common feature of autism spectrum disorder (ASD). The objectives of this analysis were to examine risk factors and clinical correlates of sensory dysfunction in preschool children with and without ASD. Children aged 2-5 years were enrolled in a multi-site case-control study. Data were collected in eight areas across the United States in three phases. Caregivers completed an interview with questions on assisted delivery, maternal alcohol use, maternal anxiety during pregnancy, pregnancy weight gain, neonatal jaundice, preterm birth, and child sensory diagnosis given by a healthcare provider. Caregivers also completed an interview and questionnaires on sensory symptoms and clinical correlates of sensory dysfunction in their child. There were 2059 children classified as ASD, 3139 as other developmental delay or disability (DD), and 3249 as population comparison (POP). Caregivers reported significantly more sensory diagnoses and sensory symptoms in children classified as ASD than DD or POP (23.7%, 8.6%, and 0.8%, respectively, for a sensory diagnosis and up to 78.7% ASD vs. 49.6% DD for sensory symptoms). Maternal anxiety during pregnancy and neonatal jaundice were significantly associated with a sensory diagnosis and certain sensory symptoms in children with ASD and DD. Children's anxiety, attention deficits/hyperactivity, and sleep problems were significantly albeit subtly correlated with both a sensory diagnosis and sensory symptoms in children with ASD and DD. These findings support sensory dysfunction as a distinguishing symptom of ASD in preschool children and identify risk factors and clinical correlates to inform screening and treatment efforts in those with atypical development.
• Content Notes:
  Author manuscript
• Subjects:
  • Female
  • Pregnancy
  • Child
  • Humans
  • Infant, Newborn
  • Child, Preschool
  • Autism Spectrum Disorder
  • Developmental Disabilities
  • Case-Control Studies
  • Jaundice, Neonatal
  More +
• Keywords:
  • anxiety
  • autism
  • jaundice
  • risk factors
  • sensory
• Source:
  Autism Research : Official Journal of the International Society for Autism Research, 2024, v. 17, no. 1
• DOI:
  https://doi.org/10.1002/aur.3074
• ISSN:
  1939-3792 ; 1939-3806
• Pubmed ID:
  38099402
• Pubmed Central ID:
  PMC11151776
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; CC/CDC HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  162-171 (18 pdf pages)
• Volume:
  17
• Issue:
  1
• Download URL:
  https://stacks.cdc.gov/view/cdc/262139/cdc_262139_DS1.pdf
• File Type:
  [PDF - 150.61 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:c5de0fed38f954571573b9e3e46bbd5430adb1037b12bab008f3d76ce2c97041de0c2123f0774e12a5773669c5c8795da46e058ce6d55c2439405e82ff4c84da