Use of Polymerase Chain Reaction to Characterize the Etiology of Culture-Negative Empyema and Parapneumonic Effusion Among Alaska Native Children-2018-2023.

Details

• Alternative Title:
  Journal of the Pediatric Infectious Diseases Society, 2025, v. 14, no. 1: Use of Polymerase Chain Reaction to Characterize the Etiology of Culture-Negative Empyema and Parapneumonic Effusion Among Alaska Native Children-2018-2023.
• Journal Article:
  Journal of the Pediatric Infectious Diseases Society
• Personal Author:
  Steinberg, Jonathan ; DeByle, Carolynn ; Westley, Benjamin ; Gotcsik, Marah ; Geis, Jesse ; Velusamy, Srinivasan ; Fischer, Marc
• Description:
  We used polymerase chain reaction (PCR) to identify bacterial infections in culture-negative pleural fluid specimens from Alaska Native children hospitalized with empyema. PCR identified ≥1 organism in 11 (79%) of 14 specimens. Streptococcus pneumoniae serotype 3 was detected in 6 specimens; all 6 participants had received 13-valent pneumococcal conjugate vaccine.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • Child, Preschool
  • Polymerase Chain Reaction
  • Male
  • Pleural Effusion
  • Female
  • Streptococcus pneumoniae
  • Child
  • Alaska Natives
  • Infant
  More +
• Keywords:
  • empyema
  • child
  • American Indian or Alaska Native
  • bacterial infections
  • Streptococcus pneumoniae
  • vaccination
• Source:
  Journal of the Pediatric Infectious Diseases Society, 2025, v. 14, no. 1
• DOI:
  https://doi.org/10.1093/jpids/piae131
• ISSN:
  2048-7193 ; 2048-7207
• Pubmed ID:
  39713952
• Pubmed Central ID:
  PMC12683488
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; CC/CDC HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  Alaska
• Pages in Document:
  piae131(8 pdf pages)
• Volume:
  14
• Issue:
  1
• Download URL:
  https://stacks.cdc.gov/view/cdc/261832/cdc_261832_DS1.pdf
• File Type:
  [PDF - 310.13 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:6df6249a2fa79effd831250ce25c5eff35169b46211a5ae5d685b2d07eac31d583ad5830446dc410c0d7cb305780f2642ff18c23059d10a630924fad1ebba285