Assessing Non-Oral PrEP Alternatives Among Young Black Women in the Southern USA.

Details

• Alternative Title:
  Journal of Racial and Ethnic Health Disparities, 2026, v. 13, no. 1: Assessing Non-Oral PrEP Alternatives Among Young Black Women in the Southern USA.
• Journal Article:
  Journal of Racial and Ethnic Health Disparities
• Personal Author:
  Denson, Damian J. ; Tesfaye, Casey Langer ; Glusberg, Daniela ; Schoua-Glusberg, Alisú ; Betley, Valerie ; Gale, Bryan ; Cardo, Jessica ; Frew, Paula M. ; McLellan-Lemal, Eleanor ; O'Connor, Siobhán M. ; McNicholl, Janet M.
• Description:
  Young Black women in the southern US face a high HIV burden. While daily oral HIV pre-exposure prophylaxis (PrEP) can effectively prevent HIV, its use is low among Black women. The acceptability of and perceived intention to use emerging PrEP products among young Black women in the southern US are not well understood. Non-oral PrEP alternatives could address challenges to PrEP uptake and reduce health disparities. We conducted virtual semi-structured interviews with Black women aged 18-34 in Atlanta, GA; Baton Rouge, LA; and Jackson, MS, to explore their perspectives on three emerging PrEP products: a long-acting injection, a subdermal implant, and a dual-purpose contraception and HIV prevention intravaginal ring. Seventy-five interviews were conducted from January to October 2021 and analyzed using inductive thematic analysis with NVivo software. Most participants were open to using medication to prevent HIV. The intravaginal ring was the most preferred, primarily due to its dual-purpose function, although it was also frequently rejected. The long-acting injection was the second most preferred and least rejected, perceived as the least invasive. The skin implant was the least preferred and most rejected, viewed as the most invasive. Our findings highlight the need for multiple PrEP options to meet individual preferences. Detailed descriptions, instructions, and experiential learning methods are crucial for choosing non-oral PrEP modalities. Practitioners should address questions and offer peer-based learning opportunities. Designing and promoting PrEP strategies for young Black women should involve close consultation with these consumers.
• Content Notes:
  Author manuscript
• Subjects:
  • Adolescent
  • Adult
  • Female
  • Humans
  • Young Adult
  • Black or African American
  • HIV Infections
  • Interviews as Topic
  • Pre-Exposure Prophylaxis
• Keywords:
  • HIV Prevention
  • PrEP
  • Black women
  • Qualitative
  • Health disparities
• Source:
  Journal of Racial and Ethnic Health Disparities, 2026, v. 13, no. 1
• DOI:
  https://doi.org/10.1007/s40615-024-02263-y
• ISSN:
  2197-3792 ; 2196-8837
• Pubmed ID:
  39760837
• Pubmed Central ID:
  PMC12228822
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; 200-2013-57341/National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention/
• Genre:
  Journal Article
• Pages in Document:
  505-516 (19 pdf pages)
• Volume:
  13
• Issue:
  1
• Download URL:
  https://stacks.cdc.gov/view/cdc/261801/cdc_261801_DS1.pdf
• File Type:
  [PDF - 444.16 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:942840dd00421672c96c392cf48b3f2146846507b683aa48675c1d9998b5dc53054aaa9febf97c5bff673f997b337fffa850295acfb1b7b8811998d3f987fa32