Characteristics of Nursing Homes With High Rates of Invasive Methicillin-resistant Staphylococcus Aureus Infections.

Details

• Alternative Title:
  Journal of the American Geriatrics Society, 2025, v. 73, no. 3: Characteristics of Nursing Homes With High Rates of Invasive Methicillin-resistant Staphylococcus Aureus Infections.
• Journal Article:
  Journal of the American Geriatrics Society
• Personal Author:
  See, Isaac ; Jackson, Kelly A. ; Hatfield, Kelly M. ; Paul, Prabasaj ; Li, Rongxia ; Nadle, Joelle ; Petit, Susan ; Ray, Susan M. ; Harrison, Lee H. ; Jeffrey, Laura ; Lynfield, Ruth ; Bernu, Carmen ; Dumyati, Ghinwa ; Gellert, Anita ; Schaffner, William ; Markus, Tiffanie ; Gokhale, Runa H. ; Stone, Nimalie D. ; Slifka, Kara Jacobs
• Description:
  Nursing home residents experience a large burden of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. Data are limited regarding nursing home characteristics associated with differences in facility-level invasive MRSA rates.
  
  We analyzed 2011-2015 data from CDC's Emerging Infections Program (EIP) active population- and laboratory-based surveillance for invasive MRSA cases within seven states. A nursing home-onset case was defined as MRSA cultured from a normally sterile site in a person living in a nursing home 3 days before culture collection. Facility rates were calculated as nursing home-onset cases per 100,000 resident-days. Nursing home resident-day denominators and facility characteristics were obtained from four Centers for Medicare & Medicaid Services (CMS) datasets. A general estimating equations model with a logit link assessed characteristics of the facilities with highest rates comprising 50% of nursing home MRSA cases ("high rates").
  
  The 626 nursing homes in the surveillance area had 2824 invasive MRSA cases; 82% of facilities had at ≥1 case. The 20% of facilities with highest rates (≥3.84 cases/100,000 resident-days) had 50% of nursing home-onset cases. In multivariable regression, facilities with high rates were more likely to have CMS-derived characteristics of presence of a resident with a multidrug-resistant organism; or greater proportions of residents who were male, were short stay (in the facility <100 days), had a nasogastric or percutaneous gastrostomy tube, or require extensive assistance with bed repositioning; and more likely to be in an EIP area with higher hospital-onset MRSA rates. Higher registered nurses staffing levels (hours/resident/day) and higher proportions of White residents were associated with lower rates.
  
  Facilities with higher invasive MRSA rates served residents with more clinical and functional care needs. Increasing registered nurse staffing in high-risk facilities might assist with reduction of invasive MRSA rates. These findings could help prioritize nursing homes for future MRSA prevention work.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • Nursing Homes
  • Methicillin-Resistant Staphylococcus aureus
  • Staphylococcal Infections
  • Male
  • Female
  • Aged
  • Cross Infection
  • Aged, 80 and over
• Keywords:
  • methicillin-resistant
  • Staphylococcus aureus
  • nursing homes
  • infection control
  • public health
  • methicillin‐resistant
• Source:
  Journal of the American Geriatrics Society, 2025, v. 73, no. 3
• DOI:
  https://doi.org/10.1111/jgs.19189
• ISSN:
  0002-8614 ; 1532-5415
• Pubmed ID:
  39829432
• Pubmed Central ID:
  PMC11907741
• Document Type:
  Text
• Funding:
  U50CK000204/CC/CDC HHSUnited States/ ; U50CK000196/CC/CDC HHSUnited States/ ; U50 CK000198/CK/NCEZID CDC HHSUnited States/ ; U50 CK000199/CK/NCEZID CDC HHSUnited States/ ; U50CK000201/CC/CDC HHSUnited States/ ; U50 CK000196/CK/NCEZID CDC HHSUnited States/ ; U50 CK000201/CK/NCEZID CDC HHSUnited States/ ; U50CK000199/CC/CDC HHSUnited States/ ; U50 CK000195/CK/NCEZID CDC HHSUnited States/ ; U50 CK000204/CK/NCEZID CDC HHSUnited States/ ; U50CK000203/CC/CDC HHSUnited States/ ; U50CK000195/CC/CDC HHSUnited States/ ; U50 CK000203/CK/NCEZID CDC HHSUnited States/ ; U50CK000198/CC/CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  849-858 (16 pdf pages)
• Volume:
  73
• Issue:
  3
• Download URL:
  https://stacks.cdc.gov/view/cdc/261757/cdc_261757_DS1.pdf
• File Type:
  [PDF - 198.88 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:8a84d827a51e3c432c73da48e154f7b9524e5b75c4ffbe2cb158e870154a9c96dbf086fe8d8ea080d956ae29563e3b43b443718bdfb81259ace8a1bf1c119672