Carbapenemase Mechanism Testing to Support Treatment, Infection Control, and Public Health: the Role of the Clinical Laboratory.

Details

• Alternative Title:
  Clinics in Laboratory Medicine, 2025, v. 45, no. 1: Carbapenemase Mechanism Testing to Support Treatment, Infection Control, and Public Health: the Role of the Clinical Laboratory.
• Journal Article:
  Clinics in Laboratory Medicine
• Personal Author:
  Blosser, Sara J. ; Bhatnagar, Amelia S. ; Bollinger, Susan ; Giffen, Samantha R.
• Description:
  Carbapenemase mechanism testing in carbapenem-resistant Enterobacterales is essential for informing patient treatment, infection prevention, and control. By highlighting the clinical and infection control imperative for this testing, addressing current barriers, and delineating future needs, we set the stage and advocate for routine carbapenemase mechanism testing in all clinical laboratories in the United States.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • beta-Lactamases
  • Bacterial Proteins
  • Infection Control
  • Enterobacteriaceae Infections
  • Public Health
  • Anti-Bacterial Agents
  • Carbapenem-Resistant Enterobacteriaceae
  • Laboratories, Clinical
  • Carbapenems
• Keywords:
  • Carbapenemase
  • Antibiotic resistance
  • CRE
  • Clinical laboratory
  • Beta-lactamase inhibitors
• Source:
  Clinics in Laboratory Medicine, 2025, v. 45, no. 1
• DOI:
  https://doi.org/10.1016/j.cll.2024.10.006
• ISSN:
  0272-2712 ; 1557-9832
• Pubmed ID:
  39892937
• Pubmed Central ID:
  PMC12338270
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  51-61 (13 pdf pages)
• Volume:
  45
• Issue:
  1
• Download URL:
  https://stacks.cdc.gov/view/cdc/261714/cdc_261714_DS1.pdf
• File Type:
  [PDF - 424.11 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:339d74f635612339514a17e09d1c4495a3d43fa8d865a7d6aefc6f29f86bbe9a7af0ce7978fda50606865b596eb30e30d55fabe3488367cb4abf866bc7709f23