Details:

Alternative Title:
Expert Rev Anti Infect Ther
Personal Author:
Guh, Alice Y ; Limbago, Brandi M ; Kallen, Alexander J ;
Guh, Alice Y ; Limbago, Brandi M ; Kallen, Alexander J ; Less -
Description:
Carbapenem-resistant Enterobacteriaceae (CRE) are multidrug-resistant organisms with few treatment options that cause infections associated with substantial morbidity and mortality. CRE outbreaks have been increasingly reported worldwide and are mainly due to the emergence and spread of strains that produce carbapenemases. In the United States, transmission of CRE is primarily driven by the spread of organisms carrying the Klebsiella pneumoniae carbapenemase enzyme, but other carbapenemase enzymes, such as the New-Delhi metallo-β-lactamase, have also emerged. Currently recommended control strategies for healthcare facilities include the detection of patients infected or colonized with CRE and implementation of measures to prevent further spread. In addition to efforts in individual facilities, effective CRE control requires coordination across all healthcare facilities in a region. This review describes the current epidemiology and surveillance of CRE in the United States and the recommended approach to prevention.
Subject:
[+]
Anti-Bacterial Agents
Article
Bacterial Proteins
Beta-Lactamases
Beta-Lactam Resistance
Carbapenems
Enterobacteriaceae
Enterobacteriaceae Infections
Epidemiological Monitoring
Humans
Sanitation

Source:
Expert Rev Anti Infect Ther. 12(5):565-580 ;
Pubmed ID:
24666262
Pubmed Central ID:
PMC6494086
Document Type:
Journal Article ;
Funding:
CC999999/Intramural CDC HHS/United States ;
Place as Subject:
United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:e7f3c0927a491fcd59185a4d3e34646bf8881bb28ad1ceea3fe950cd1a49b623
File Type:

Supporting Files

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