Heterogeneous Fe-N-C Cocatalyst For Hydroquinone Oxidation Enables Aerobic Oxidation of Primary Alcohols to Aldehydes.

Details

• Alternative Title:
  Angewandte Chemie (International Ed. in English), 2025, v. 64, no. 20: Heterogeneous Fe-N-C Cocatalyst For Hydroquinone Oxidation Enables Aerobic Oxidation of Primary Alcohols to Aldehydes.
• Journal Article:
  Angewandte Chemie (International Ed. in English)
• Personal Author:
  Hoque, Md Asmaul ; Schweinzer, Clara ; Martinez, Jesse J. ; Tewes, Friederike ; Sacchetti, Vittorio ; Grützmacher, Hansjörg ; Stahl, Shannon S
• Description:
  Benzoquinone (BQ) is commonly used as a cocatalyst in multi-component catalyst systems for aerobic oxidation of organic molecules. Such methods often proceed by a redox cascade in which a secondary catalyst supports aerobic oxidation of hydroquinone (HQ) to BQ. The present study shows that a commercially available non-precious metal heterogeneous catalyst, PAJ-Fe-N-C, is much more efficient than established homogeneous catalysts for aerobic oxidation of HQ to BQ, and this improved reactivity is crucial to support aerobic oxidation of primary alcohols to aldehydes with the homogeneous iridium catalyst, Ir(trop2DADOTf (trop2DAD = N,N-bis(5-H-dibenzoa,dcycloheptene-5-yl)-1,4-diazabuta-1,3-diene). The combination of this heterogeneous/homogeneous catalyst system operates with Ir catalyst loadings as low as 0.05 mol % and turnover frequencies ≥350 h−1.
• Content Notes:
  Author manuscript
• Subjects:
  • Hydroquinones
  • Iridium
  • Benzoquinones
  • Aldehydes
  • Oxidation-Reduction
• Keywords:
  • Aerobic
  • alcohol oxidation
  • benzoquinone
  • catalysis
  • aldehydes
• Source:
  Angewandte Chemie (International Ed. in English), 2025, v. 64, no. 20
• DOI:
  https://doi.org/10.1002/anie.202424778
• ISSN:
  1433-7851 ; 1521-3773
• Pubmed ID:
  39979222
• Pubmed Central ID:
  PMC12070451
• Document Type:
  Text
• Funding:
  S10 OD020022/OD/NIH HHSUnited States/ ; S10 OD020022/CD/ODCDC CDC HHSUnited States/ ; DE-FG02-05ER15690/Basic Energy Sciences/ ; 20020 181966/SNSF_/Swiss National Science FoundationSwitzerland/ ; R35 GM134929/GM/NIGMS NIH HHSUnited States/ ; CHE-1048642/National Science Foundation/
• Genre:
  Journal Article
• Pages in Document:
  12 pdf pages
• Volume:
  64
• Issue:
  20
• Download URL:
  https://stacks.cdc.gov/view/cdc/261665/cdc_261665_DS1.pdf
• File Type:
  [PDF - 1.05 MB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:44358bacc05235346a6f750349e662b06b90afcf7ee59f284c0217ce6cd7642fda75206c06b008e14bc5db4ae4182db8d1c6d0fd04e9640c85380d3f1aa1ec8f