Renal Cell Carcinoma in a Common Marmoset: First Report and a Brief Review of Nonhuman Primate Literature.

Details

• Alternative Title:
  Journal of Medical Primatology, 2025, v. 54, no. 2: Renal Cell Carcinoma in a Common Marmoset: First Report and a Brief Review of Nonhuman Primate Literature.
• Journal Article:
  Journal of Medical Primatology
• Personal Author:
  Battee, Taysia ; Gonzalez, Olga ; Medlin, Phil S. ; Dick, Edward J. ; Shivanna, Vinay
• Description:
  Renal cell carcinoma (RCC) is a malignant form of urogenital cancer that arises from renal tubular epithelial cells. Here, we describe a case of renal cell carcinoma in a common marmoset (Callithrix jacchus). Immunohistochemistry demonstrated positive reactivity for PAX8 and CD10 in the renal neoplasm. We review 115 cases of spontaneous renal tumors in nonhuman primates (NHP) reported in the literature and from the Southwest National Primate Research Center records. Across all NHPs, malignant renal neoplasms were more frequent than benign. There appears to be a male sex predilection for renal tumors in baboons. This is the first reported case of renal cell carcinoma in a marmoset.
• Content Notes:
  Author manuscript
• Subjects:
  • Animals
  • Callithrix
  • Carcinoma, Renal Cell
  • Kidney Neoplasms
  • Monkey Diseases
  • Male
  • Female
• Keywords:
  • neoplasm
  • tumor
  • kidney
  • non-human primate
  • marmoset
• Source:
  Journal of Medical Primatology, 2025, v. 54, no. 2
• DOI:
  https://doi.org/10.1111/jmp.70014
• ISSN:
  0047-2565 ; 1600-0684
• Pubmed ID:
  40148737
• Pubmed Central ID:
  PMC12050988
• Document Type:
  Text
• Funding:
  P51 OD011133/OD/NIH HHSUnited States/ ; S10 OD028732/OD/NIH HHSUnited States/ ; P51 OD011133/CD/ODCDC CDC HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  e70014 (13 pdf pages)
• Volume:
  54
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/261559/cdc_261559_DS1.pdf
• File Type:
  [PDF - 1.10 MB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:90d0af73df9fc7340d2a6cb756a418a475a36cf4bcd97b38c67cfc200b40f5b03f28e918998d77b3526892a92f49d5e40365bf165fd1cdc3fb66760aecfd09c8