Pseudomonas Infections in the Common Marmoset (Callithrix Jacchus): Gross and Histopathological Findings.

Details

• Alternative Title:
  Journal of Medical Primatology, 2025, v. 54, no. 2: Pseudomonas Infections in the Common Marmoset (Callithrix Jacchus): Gross and Histopathological Findings.
• Journal Article:
  Journal of Medical Primatology
• Personal Author:
  Silva, Victoria D ; Shridhar, Pragathi B ; Gonzalez, Olga D ; Dick, Edward J ; Shivanna, Vinay
• Description:
  Common marmosets (Callithrix jacchus) are a New World nonhuman primate (NHP) whose popularity as a research model continues to expand. Marmosets were identified as the predominant NHP species that is susceptible to spontaneous Pseudomonas infections based on a 27-year survey in a primate colony, encompassing several NHP species. 26 common marmosets were retrospectively identified and evaluated for spontaneous Pseudomonas spp. infections. Clinical symptoms included lethargy, weight loss, gastrointestinal issues (diarrhea, bloating, vomiting, poor appetite), increased respiratory effort, and difficulty urinating. Affected organs (larynx, lungs, liver, gallbladder, intestines, colon, uterus, and urinary bladder) appeared discolored, distended, or enlarged. Microscopic findings included inflammatory infiltrates, edema, necrosis, hemorrhage, and pseudomembranous lesions. Only animals with clinical symptoms or gross evidence of bacterial infection were cultured; therefore, the actual incidence of Pseudomonas spp. infections is unknown. We present the common and uncommon lesions associated with Pseudomonas infections in the common marmoset.
• Content Notes:
  Author manuscript
• Subjects:
  • Animals
  • Callithrix
  • Pseudomonas Infections
  • Monkey Diseases
  • Female
  • Male
  • Pseudomonas
  • Retrospective Studies
• Keywords:
  • cholangiohepatitis
  • cholecystitis
  • colitis
  • enteritis
  • pneumonia
  • Pseudomonas
  • typhlitis
  • non-human primate
  • natural disease
  • marmoset
  More +
• Source:
  Journal of Medical Primatology, 2025, v. 54, no. 2
• DOI:
  https://doi.org/10.1111/jmp.70016
• ISSN:
  0047-2565 ; 1600-0684
• Pubmed ID:
  40166954
• Pubmed Central ID:
  PMC11975447
• Document Type:
  Text
• Funding:
  P51 OD011133/OD/NIH HHSUnited States/ ; S10 OD028732/OD/NIH HHSUnited States/ ; S10OD028732/NIH Office of the Director/ ; P51 OD011133/CD/ODCDC CDC HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  e70016 (14 pdf pages)
• Volume:
  54
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/261535/cdc_261535_DS1.pdf
• File Type:
  [PDF - 1.14 MB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:24838baa415ae1a5e2c140ba444d631412572a9fa181c344270710283ecc859a4eadceb960cce6dfe1da466f2eaa73aabb408124e4a6c9d42c71df7db67fe499