World Trade Center (WTC) Exposures and Cardiometabolic Risk Among WTC Health Program General Responders

Details

• Journal Article:
  American Journal of Public Health
• Personal Author:
  Krasnov, Helena ; Patel, Krupa Ambalal ; Knobel, Pablo ; Hsu, Hsiao-Hsien L. ; Teitelbaum, Susan L. ; McLaughlin, Mary A. ; Just, Allan C. ; Sade, Maayan Y.
• Description:
  Objectives. To assess the association between World Trade Center (WTC) exposures, cardiometabolic diseases (CMDs), and trajectories of glucose and systolic blood pressure (SBP) among WTC Health Program general responders (WTHPGR). Methods. We included monitoring visits (2003-2021) of WTHPGR who participated in the operations in New York City after the September 11, 2001, attack (n = 47 795). The WTC Health Program assessed WTC exposures using questionnaires and measured trajectories during monitoring study visits; CMDs were self-reported. We assessed associations with CMDs (hazard ratios and their corresponding 95% confidence intervals [CIs]) using survival analyses. We assessed associations with trajectories (odds ratios and their corresponding 95% CIs) using logistic regressions. Results. Interquartile range (IQR) increases in the number of days on-site in the 9 months following the attack were associated with increased diabetes (1.057; 95% CI = 1.025, 1.089) and hypertension (1.035; 95% CI = 1.014, 1.057) risks. IQR increases in hours on-site during September 2001 were associated with worsening glucose (1.040; 95% CI = 1.017, 1.064) and SBP (1.006; 95% CI = 1.001, 1.010) trajectories. Conclusions. WTC exposures are associated with higher CMD risk and worsening cardiometabolic trajectories among WTHPGR. Public Health implications. Linking WTC exposures to emerging diseases is vital because of its impact on health care costs and treatment access among WTHPGR.
• Subjects:
  Diabetes Mellitus Emergency Responders Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  World Trade Center; WTC; Metabolic disorders; Cohort studies; Blood sugar disorders; Diabetes; Blood pressure; Disaster response; Emergency responders; Medical monitoring; Health care
• Source:
  Am J Public Health 2025 Jul; 115(7):1120-1128
• ISSN:
  0090-0036
• Document Type:
  Text
• Funding:
  Cooperative Agreement ; Contract
• Genre:
  Journal Article
• Place as Subject:
  New York ; Rhode Island ; New York City Region [OSHA] ; Boston Region [OSHA]
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  9 pdf pages
• Volume:
  115
• Issue:
  7
• NIOSHTIC Number:
  nn:20071522
• Contact Point Address:
  Helena Krasnov, 17 E. 102nd St, CAM Building, 3 West, One Gustave L. Levy Place, Box 1057, New York, NY 10029
• Email:
  helena.furman@mssm.edu
• Federal Fiscal Year:
  2025
• Performing Organization:
  State University of New York Stony Brook
• Peer Reviewed:
  True
• Start Date:
  20040715
• End Date:
  20110630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:63dfe550392e028859336981ced978ccbb668f6b3d3873788d3ee74c2a7af189ccef6adc093b88a20d3a5471357642f071785cfe0b8e29a7988bcb10bace94f2
• Download URL:
  https://stacks.cdc.gov/view/cdc/259118/cdc_259118_DS1.pdf
• File Type:
  [PDF - 1.06 MB ]