Occupational Immunotoxicology [chapter, 2026]

Details

• Personal Author:
  Anderson, Stacey E. ; Weatherly, Lisa M. ; Meade, B. Jean
• Description:
  Individuals working in a variety of occupational industries and sectors are potentially exposed to biological, chemical, and hazardous agents with dermal and respiratory being the two most common routes of exposure. These exposures can potentially result in numerous diseases and can adversely affect an individual's health and capacity to perform at work resulting in significant economic losses. Occupational immune diseases are some of the most common illnesses that affect workers including inflammation, allergy, respiratory disease, autoimmunity, or other immune modulation resulting in suppression following exposure in the work environment. Due to the complexity of the immune system, the identification of agents that induce immunotoxicity requires specific assays. Various organizations have proposed different approaches to immunotoxicity testing that include validated immune testing protocols that measure diverse immunological biomarkers and endpoints. This chapter provides descriptions of the most commonly recognized occupational immune diseases.
• Subjects:
  Asthma, Occupational Autoimmune Diseases Occupational Health Respiratory System Respiratory Tract Diseases Safety Silicosis
• Keywords:
  Immune reaction; Immunotoxins; Toxicology; Autoimmune diseases; Allergies; Work-related asthma; WRA; Occupational hazards; Respiratory diseases; Contact dermatitis; Biomarkers; Silicosis
• Source:
  Comprehensive toxicology, fourth edition. Volume 5b: Immune system toxicology. Burns Naas LA, McQueen CA, eds. Cambridge, MA: Elsevier, 2026 Jan; 5b:50-68
• ISBN:
  9780323954884
• Publisher:
  Elsevier
• Document Type:
  Text
• Genre:
  Chapter
• Place as Subject:
  West Virginia ; Philadelphia Region [OSHA]
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  22 pdf pages
• Volume:
  5
• NIOSHTIC Number:
  nn:20071477
• Editor(s):
  McQueen, Charlene A. ; Burns Naas, Leigh Ann
• Federal Fiscal Year:
  2026
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:003492789a7101f663e3a8c8a161d65fc9ee65c9ea3ff65418325bb0588fc05d5db228b363a5410f8785aaacbcf9b0c4ad10d01091f66a6bb021f32e35bc80de
• Download URL:
  https://stacks.cdc.gov/view/cdc/259075/cdc_259075_DS1.pdf
• File Type:
  [PDF - 796.19 KB ]