Multidrug-Resistant and Methicillin-Resistant Staphylococcus aureus (MRSA) in Hog Slaughter and Processing Plant Workers and Their Community in North Carolina (USA)

Details

• Journal Article:
  Environ Health Perspect
• Personal Author:
  Neyra, Ricardo C. ; Frisancho, Jose A. ; Rinsky, Jessica L. ; Resnick, Carol ; Carroll, Karen C. ; Rule, Ana M. ; Ross, Tracy ; You, Yaqi ; Price, Lance B. ; Silbergeld, Ellen K.
• Description:
  Use of antimicrobials in industrial food-animal production is associated with the presence of antimicrobial-resistant Staphylococcus aureus (S. aureus) among animals and humans. Hog slaughter/processing plants process large numbers of animals from industrial animal operations and are environments conducive to the exchange of bacteria between animals and workers.|We compared the prevalence of multidrug-resistant S. aureus (MDRSA) and methicillin-resistant S. aureus (MRSA) carriage among processing plant workers, their household members, and community residents.|We conducted a cross-sectional study of hog slaughter/processing plant workers, their household members, and community residents in North Carolina. Participants responded to a questionnaire and provided a nasal swab. Swabs were tested for S. aureus, and isolates were tested for antimicrobial susceptibility and subjected to multilocus sequence typing.|The prevalence of S. aureus was 21.6%, 30.2%, and 22.5% among 162 workers, 63 household members, and 111 community residents, respectively. The overall prevalence of MDRSA and MRSA tested by disk diffusion was 6.9% and 4.8%, respectively. The adjusted prevalence of MDRSA among workers was 1.96 times (95% CI: 0.71, 5.45) the prevalence in community residents. The adjusted average number of antimicrobial classes to which S. aureus isolates from workers were resistant was 2.54 times (95% CI: 1.16, 5.56) the number among isolates from community residents. We identified two MDRSA isolates and one MRSA isolate from workers as sequence type 398, a type associated with exposure to livestock.|Although the prevalence of S. aureus and MRSA was similar in hog slaughter/processing plant workers and their household and community members, S. aureus isolates from workers were resistant to a greater number of antimicrobial classes. These findings may be related to the nontherapeutic use of antimicrobials in food-animal production.
• Subjects:
  Animals Cross-Sectional Studies Livestock Meat-Packing Industry Methicillin-Resistant Staphylococcus Aureus Swine
• Keywords:
  Animals; Food; Livestock-foods; Livestock; Livestock-industry; Microbiology; Bacteria; Food-processing-industry; Food-processing; Questionnaires; Statistical-analysis; Pathogenicity; Meat-handlers; Meat-packing-industry
• Source:
  Environ Health Perspect. 122(5):471-477.
• Pubmed ID:
  24508836
• Pubmed Central ID:
  PMC4014760
• Document Type:
  Text
• Funding:
  5R21OH009829/OH/NIOSH CDC HHS/United States ; T32ES007018/ES/NIEHS NIH HHS/United States
• Genre:
  Journal Article
• Place as Subject:
  District of Columbia ; Maryland ; North Carolina ; OSHA Region 3 ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  7 pdf pages
• Volume:
  122
• Issue:
  5
• NIOSHTIC Number:
  nn:20045484
• Federal Fiscal Year:
  2014
• Performing Organization:
  Johns Hopkins University - Baltimore
• Peer Reviewed:
  True
• Collection(s):
  CDC Public Access National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2b7788b0d0d9e035acda836b84a5534ae3f5e8bf493641aa6b31dbc39e0462fafdcb0355029b4e72b607c1a1110168b97698002b398e00dcdc19a367ac97c960
• Download URL:
  https://stacks.cdc.gov/view/cdc/25596/cdc_25596_DS1.pdf
• File Type:
  [PDF - 261.66 KB ]