Prevention Strategies for Monkeypox, including Vaccinating People at Risk via Sexual Exposure, for U.S. Travelers Visiting Countries with Clade I Monkeypox Outbreaks [September 23, 2024, 12:45 PM ET]

Details

• Corporate Authors:
  Centers for Disease Control and Prevention (U.S.). Health Alert Network (HAN)
• Description:
  CDCHAN-00516: The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Update to provide additional information about the ongoing outbreak of clade I monkeypox virus (MPXV), the virus that causes monkeypox, in Central and Eastern Africa. This report is an update to HAN Health Advisory 501 issued in December 2023 and HAN Health Update 513 in August 2024. MPXV transmission in countries where the virus is endemic is typically via exposure to infected wildlife with subsequent person-to-person spread via close contact (including intimate or sexual contact) with a person with monkeypox, or direct contact with their respiratory secretions (e.g., snot, mucus) or contaminated objects (e.g., bedding). During the global clade II outbreak, human-to-human transmission of monkeypox has been predominantly spreading through sexual contact. During 2024, the Democratic Republic of the Congo (DRC) has reported >21,000suspected clade I monkeypox cases, its largest annual number on record. Although the proportion of people impacted in DRC (population >99 million) is relatively low, cases are more widespread than in any previously reported DRC outbreak. Clade Ia monkeypox cases are impacting the western part of DRC (particularly the rural Équateur Province). No cases of clade Ia monkeypox have been reported outside Central African countries where clade Ia MPXV is endemic. Clade Ib monkeypox cases are impacting the eastern part of DRC and have been spread through regional travel. Early data indicate that a large proportion of clade Ib monkeypox cases among adults has been associated with sexual contact, including via ongoing transmission believed to be occurring in some countries where the virus is not normally found. Travelers to DRC or other countries with sustained spread of clade I monkeypox should be made aware of activities associated with cases and should be vaccinated with two doses of JYNNEOS if they anticipate certain sexual exposures while traveling. Active monitoring for monkeypox continues to occur in the United States. Although the United States continues to be affected by an ongoing global outbreak of clade II monkeypox that began in 2022, no domestic cases of clade I monkeypox have been identified in the United States at this time. Continue to follow CDC’s current vaccine guidance to prevent clade II MPXV infection, which continues to circulate in the United States, and will also help protect against clade I MPXV.
• Content Notes:
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  Health Alert: Requires immediate action or attention, highest level of importance.
  
  Health Advisory: May not require immediate action; provides important information for a specific incident or situation.
  
  Health Update: Unlikely to require immediate action; provides updated information regarding an incident or situation.
  
  HAN Info Service: Does not require immediate action; provides general public health information.
  
  
• Subjects:
  Disaster Planning Disease Transmission, Infectious Emergencies Endemic Diseases Health Communication Monkeypox Virus Mpox, Monkeypox Vaccination
• Keywords:
  Advisories Alerts Clade 1b MPXV HAN Health Alert Network MPXV Updates
• Series:
  Health Alert Network
• Subseries:
  CDC Health Advisory
• Publisher:
  Centers for Disease Control and Prevention (CDC) (U.S.)
• Document Type:
  Text
• Genre:
  Alert
• Place as Subject:
  Democratic Republic of Congo ; The Republic of Congo ; Central African Republic ; Angola ; Zambia ; Rwanda ; Burundi ; Uganda ; South Sudan
• Rights:
  Public Domain
• CIO:
  Office of Emergency Risk Communication (OERC)
• Pages in Document:
  6 pdf pages
• Issue:
  516
• Collection(s):
  Health Alert Network (HAN)
• Main Document Checksum:
  urn:sha-512:4a47b3fa3c0f680b8ab75000f07eb8cd8e80c72b75a44fed75f89b0c7c21ff629e11e2d93235d07f8305407ee5c8d58e80c3c956235176bc6d4b22dc4e33dbe6
• Download URL:
  https://stacks.cdc.gov/view/cdc/255116/cdc_255116_DS1.pdf
• File Type:
  [PDF - 224.65 KB ]