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Mpox Caused by Human-to-Human Transmission of Monkeypox Virus in the Democratic Republic of the Congo with Spread to Neighboring Countries [August 7, 2024, 3:15 PM ET]

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  • Description:
    CDCHAN-00513: The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Update to provide additional information about the outbreak of monkeypox virus (MPXV) in the Democratic Republic of the Congo (DRC); the first Health Advisory about this outbreak was released in December 2023.

    Since January 2023, the DRC has reported the largest number of yearly suspected clade I monkeypox cases on record. While clade I MPXV is endemic, or naturally occurring, in DRC, the current outbreak is more widespread than any previous DRC outbreak and has resulted in clade I monkeypox transmission to some neighboring countries. The Republic of the Congo (ROC), which borders DRC to the west, declared a clade I monkeypox outbreak in April 2024, and there have been confirmed cases in the Central African Republic (CAR). While clade I monkeypox is endemic in ROC and CAR, the epidemiologic pattern of recent cases suggests a possible link to DRC.

    In late July 2024, Burundi, Rwanda, and Uganda, which sit on the eastern border of DRC, reported confirmed cases of monkeypox, with some cases having linkages to DRC. Rwanda and Uganda have confirmed these cases are due to clade IMPXV; in Burundi, clade-specific testing is underway, but cases are presumed to be clade I due to DRC’s proximity. Monkeypox is not known to be endemic in these countries.

    No cases of clade I monkeypox have been reported outside central and eastern Africa at this time. Because there is a risk of additional spread, CDC recommends clinicians and jurisdictions in the United States maintain a heightened index of suspicion for monkeypox in patients who have recently been in DRC or to any country sharing a border with DRC (ROC, Angola, Zambia, Rwanda, Burundi, Uganda, South Sudan, CAR) and present with signs and symptoms consistent with monkeypox. These can include: rash that may be located on the hands, feet, chest, face, mouth, or near the genitals; fever; chills; swollen lymph nodes; fatigue; myalgia (muscle aches and backache); headache; and respiratory symptoms like sore throat, nasal congestion, and cough.

  • Content Notes:
    Notice of Possible Alert Expiration: The CDC Health Alert, Advisory, Update, and Info Service announcements, distributed by the Health Alert Network (HAN), were active on the date they were originally published. Publication dates have been added to Titles for clarity. A CDC Health Alert, Advisory, Update, and Info Service announcement may expire at any time. They may also be updated or superseded according to later developments. None of the CDC Health Alert, Advisory, Update, or Info Service announcements in the Stacks HAN Collection should be assumed to be current or active. Stacks preserves HAN announcements in order to maintain a record of past CDC actions. Stacks in not designed for up-to-the-minute notifications. For the list of current CDC Health Alert, Advisory, Update, or Info Service announcements, patrons should visit the Health Alert Network (HAN) webpage at https://www.cdc.gov/han/php/about/index.html. For up to the minute reports, subscribe to the HAN email alert system hosted by CDC News & Updates at https://tools.cdc.gov/campaignproxyservice/subscriptions.aspx?topic_id=USCDC_486

    Categories of Health Alert Network (HAN) messages:

    Health Alert: Requires immediate action or attention, highest level of importance.

    Health Advisory: May not require immediate action; provides important information for a specific incident or situation.

    Health Update: Unlikely to require immediate action; provides updated information regarding an incident or situation.

    HAN Info Service: Does not require immediate action; provides general public health information.

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    Public Domain
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  • Pages in Document:
    5 pdf pages
  • Issue:
    513
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  • Main Document Checksum:
    urn:sha-512:5b3da4d63d6b6ed78face21902cf5778aa23e6a8dcda3d548e013dbe2d8715d992979b211864c5d4deb7c42f9211d9b01f9a2e1d107bbd16b47988fc670b7253
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File Language:
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