Pathomechanics of peripheral nerve loading: evidence in carpal tunnel syndrome.

Details

• Personal Author:
  Keir PJ ; Rempel DM
• Description:
  Peripheral nerve injury is a common occurrence, with carpal tunnel syndrome (CTS) receiving the most attention. Nerve dysfunction associated with compression syndromes results from an interruption or localized interference of microvascular function due to structural changes in the nerves or surrounding tissues. This article reviews the physiologic, pathophysiologic, and histologic effects of compressing peripheral nerves in animal models, and then examines the evidence for similar processes in humans using CTS as a model. [Description provided by NIOSH]
• Subjects:
  Animals Histology Musculoskeletal Diseases Musculoskeletal System Occupational Health Safety
• Keywords:
  Nerve damage; Neurological system; Carpal tunnel syndrome; CTS; Physiopathology; Physiological effects; Histology; Animal studies; Upper extremities
• ISSN:
  0894-1130
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  259-269
• Volume:
  18
• Issue:
  2
• NIOSHTIC Number:
  nn:20065870
• Citation:
  J Hand Ther 2005 Apr-Jun; 18(2):259-269
• Contact Point Address:
  Peter J. Keir, PhD, School of Kinesiology and Health Science, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada
• Email:
  pjkeir@yorku.ca
• Federal Fiscal Year:
  2005
• Performing Organization:
  University of California - San Francisco
• Peer Reviewed:
  True
• Start Date:
  20010701
• Source Full Name:
  Journal of Hand Therapy
• End Date:
  20060630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:15aef4a67480b91cef4bf0c719ba3f6846e99a2aec7a3311a9ac5fe3c95427f3596f09f0a96dcff040ff19f1ccb0d0d2546df9d476c3d896d793e529f993f4da
• Download URL:
  https://stacks.cdc.gov/view/cdc/249580/cdc_249580_DS1.pdf
• File Type:
  [PDF - 2.57 MB ]