Effectiveness of portable HEPA air cleaners on reducing indoor PM2.5 and NH3 in an agricultural cohort of children with asthma: a randomized intervention trial.

Details

• Personal Author:
  Farquhar SA ; Hardie DC ; Jansen KL ; Karr CJ ; Krenz JE ; Perez A ; Riederer AM ; Sampson PD ; Tchong-French MI ; Torres E ; Younglove LR
• Description:
  We conducted a randomized trial of portable HEPA air cleaners with pre-filters designed to also reduce NH3 in non-smoking homes of children age 6-12 with asthma in Yakima Valley (Washington, USA). Participants were recruited through the Yakima Valley Farm Workers Clinic asthma education program. All participants received education on home triggers while intervention families additionally received two HEPA cleaners (child's sleeping area, main living area). Fourteen-day integrated samples of PM2.5 and NH3 were measured at baseline and one-year follow-up. We fit ANCOVA models to compare follow-up concentrations in HEPA vs control homes, adjusting for baseline concentrations. Seventy-one households (36 HEPA, 35 control) completed the study. Most were single-family homes, with electric heat and stove, A/C, dogs/cats, and mean (SD) 5.3 (1.8) occupants. In the sleeping area, baseline geometric mean (GSD) PM2.5 was 10.7 (2.3) µg/m3 (HEPA) vs 11.2 (1.9) µg/m3 (control); in the living area, it was 12.5 (2.3) µg/m3 (HEPA) vs 13.6 (1.9) µg/m3 (control). Baseline sleeping area NH3 was 62.4 (1.6) µg/m3 (HEPA) vs 65.2 (1.8) µg/m3 (control). At follow-up, HEPA families had 60% (95% CI, 41%-72%; p < .0001) and 42% (19%-58%; p = .002) lower sleeping and living area PM2.5, respectively, consistent with prior studies. NH3 reductions were not observed. [Description provided by NIOSH]
• Subjects:
  Agriculture Air Pollution Air Pollution, Indoor Asthma Asthma, Occupational Environmental Exposure Family Farmers Occupational Health Safety
• Keywords:
  Agricultural Industry; Agriculture; Children; Environmental Exposure; Farm Workers; Families; Air Quality; Asthma; Indoor Air Pollution; HEPA Filters; High-efficiency Particulate Air Filters; Author Keywords: Asthma; Children; HEPA Cleaners; NH3; PM2.5; Randomized Trial
• ISSN:
  0905-6947
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  454-466
• Volume:
  31
• Issue:
  2
• NIOSHTIC Number:
  nn:20065431
• Citation:
  Indoor Air 2021 Mar; 31(2):454-466
• Contact Point Address:
  Anne M. Riederer, Department of Environmental & Occupational Health Sciences, University of Washington, 4225 Roosevelt Way NE, Seattle, WA 98105, USA
• Email:
  anneried@uw.edu
• CAS Registry Number:
  Ammonia (CAS RN 7664-41-7)
• Federal Fiscal Year:
  2021
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20010930
• Source Full Name:
  Indoor Air
• End Date:
  20270929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0d2c63324f85076a88fab6e780de8a1405bb595801551066c3b3f9603a7a521e4300aed69b8c82e2cd176dffdd1bce5e39a5e75f0fb66231ac2fb5ed96ee9f55
• Download URL:
  https://stacks.cdc.gov/view/cdc/249435/cdc_249435_DS1.pdf
• File Type:
  [PDF - 393.12 KB ]