Estimation of the deposition of ultrafine 3D printing particles in human tracheobronchial airways.

Details

• Personal Author:
  Chen Y ; Su W-C ; Xi J
• Description:
  3D printers have been widely used as a tool for prototype manufacturing in industries, schools, and homes. During operation, 3D printers emit ultrafine particles that could be inhaled by the user and induce adverse health effects. Thus, exposure to ultrafine 3D-printing generated particles has drawn the attention of occupational and environmental health researchers. In this study, a recently developed Mobile Aerosol Lung Deposition Apparatus (MALDA) was applied to investigate the respiratory deposition of ultrafine 3D printing particles. The MALDA consists of a set of representative human airway replicas from mouth, throat, trachea, down to the bronchiolar airways of the 11th bifurcation generation. A series of respiratory deposition experiments were carried out in the laboratory using the MALDA and a desktop 3D printer to estimate the deposition of ultrafine 3D printing particles in individual generations of the lung. Results showed that the cumulative deposition from the 1st to 11th bifurcation generations was found to be 1%-13% depending on the particle size, which was slightly less than the respiratory deposition predicted from the conventional deposition curve. [Description provided by NIOSH]
• Subjects:
  Aerosols Occupational Health Particulate Matter Printing Printing, Three-Dimensional Respiratory System Safety
• Keywords:
  Author Keywords: Ultrafine Particles; 3D Printer; Respiratory Deposition; Bifurcation Generation Three Dimensional Printing; 3D Printing; Printers; Printer-emitted Particles; Ultrafine Particles; Particle Size; Chemical Deposition; Inhalation; Aerosols;
• ISSN:
  0021-8502
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1 ; OSHA Region 6 ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  149
• NIOSHTIC Number:
  nn:20065102
• Citation:
  J Aerosol Sci 2020 Nov; 149:105605
• Contact Point Address:
  Wei-Chung Su, Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas, Health Science Center at Houston, 1200 Pressler St. Houston, TX 77030, USA
• Email:
  Wei-Chung.Su@uth.tmc.edu
• Federal Fiscal Year:
  2021
• Performing Organization:
  University of Texas Health Science Center, Houston
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Aerosol Science
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a7e792d92009a9563e250a7752e09dfe2f61f73ae8c82cc057cbd68ffe77d229f7fd749841ee7c27d3071059f5309934f1591ba082570f8736f335da3ecadb05
• Download URL:
  https://stacks.cdc.gov/view/cdc/249334/cdc_249334_DS1.pdf
• File Type:
  [PDF - 1.66 MB ]