Bone lead measurements of live condors in field to assess cumulative lead exposure.

Details

• Personal Author:
  Hauck TJ ; McClure CJW ; Parish CN ; Sayam ASM ; Specht AJ ; Watson RT ; Weisskopf MG
• Description:
  Lead poisoning remains the leading cause of diagnosed death for critically endangered California condors, which are annually monitored for lead exposure via blood tests. Blood tests are generally reflective of acute lead exposure. Since condors are victims to both chronic and acute lead exposure, measuring bone, which in humans is reflective of years to decades worth of exposure, is a valuable biomarker. In this study, we measured bone Pb of the tibiotarsus of 64 condors in vivo using a portable x-ray fluorescence device. The average uncertainty for measurements, typically reflective of how effective the device performed, was found to be 3.8 +/- 2.2 µg/g bone mineral. The average bone lead level was found to be 26.7 +/- 24.5 µg/g bone mineral. Bone lead correlated significantly with a sum of all blood lead measures over the lifetime of each condor. In the future, bone lead can potentially be used to inform treatment planning and address the chronic health implications of lead in the species. [Description provided by NIOSH]
• Subjects:
  Biomarkers Environmental Exposure Environmental Pollution Lead Occupational Exposure Occupational Health Safety
• Keywords:
  Author Keywords: Bone; Cumulative; Lead; Portable XRF; Serial Blood Lead Blood Lead Levels; X-ray Fluorescence Analysis; Environmental Pollution; Environmental Contamination; Chronic Exposure; Biomarkers; In Vivo Study;
• ISSN:
  0944-1344
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Idaho ; Indiana ; Massachusetts ; OSHA Region 1 ; OSHA Region 10 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20070141
• Citation:
  Environ Sci Pollut Res 2024 Sep; :[Epup ahead of print]
• Contact Point Address:
  Aaron J. Specht, School of Health Sciences, Purdue University, West Lafayette, IN, 47907, USA
• Email:
  aspecht@purdue.edu
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  2024
• Performing Organization:
  Purdue University
• Peer Reviewed:
  True
• Start Date:
  20210901
• Source Full Name:
  Environmental Science and Pollution Research
• End Date:
  20220731
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/248314/cdc_248314_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]