Details:

Alternative Title:
PLoS Negl Trop Dis
Publisher's site:
http://dx.doi.org/10.1371/journal.pntd.0002858
Personal Author:
Zapata, Juan C. ; Cox, Dermot ; Salvato, Maria S.
Zapata, Juan C. ; Cox, Dermot ; Salvato, Maria S. Less -
Description:
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that are preferentially induced by the more pathogenic members of the families Flaviviridae, Bunyaviridae, Arenaviridae, and Filoviridae. A systematic search was performed through the main medical electronic databases using as parameters all current findings concerning platelets in VHF. Additionally, the review contains information from conference proceedings.
Subject:
[+]
Blood Platelets
Hemorrhagic Fevers, Viral
Host-Pathogen Interactions
Humans
RNA Viruses

Source:
PLoS Negl Trop Dis. 2014; 8(6).
Document Type:
Journal Article
Funding:
5RC2CA149001/CA/NCI NIH HHS/United States ; AI068961/AI/NIAID NIH HHS/United States
5RC2CA149001/CA/NCI NIH HHS/United States ; AI068961/AI/NIAID NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:4527b80076d562a4b90e774669fbd4e9a296556aa3361fa7d32199916115e920
File Type:

Supporting Files

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  	license.txt	txt
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