Details:

Alternative Title:
PLoS One
Publisher's site:
http://dx.doi.org/10.1371/journal.pone.0103419
Personal Author:
McCollum, Andrea M.; Holman, Robert C.; Hughes, Christine M.; Mehal, Jason M.; Folkema, Arianne M.; ... More +
McCollum, Andrea M.; Holman, Robert C.; Hughes, Christine M.; Mehal, Jason M.; Folkema, Arianne M.; Redd, John T.; Cheek, James E.; Damon, Inger K.; Reynolds, Mary G.; Less -
Description:
Background Molluscum contagiosum virus (MCV) causes an innocuous yet persistent skin infection in immunocompetent individuals and is spread by contact with lesions. Studies point to atopic dermatitis (AD) as a risk factor for MCV infection; however, there are no longitudinal studies that have evaluated this hypothesis. Methods Outpatient visit data from fiscal years 2001–2009 for American Indian and Alaska Native (AI/AN) children were examined to describe the incidence of molluscum contagiosum (MC). We conducted a case-control study of patients <5 years old at an Indian Health Service (IHS) clinic to evaluate dermatological risk factors for infection. Results The incidence rate for MC in children <5 years old was highest in the West and East regions. MC cases were more likely to have a prior or co-occurring diagnosis of eczema, eczema or dermatitis, impetigo, and scabies (p<0.05) compared to controls; 51.4% of MC cases had a prior or co-occurring diagnosis of eczema or dermatitis. Conclusions The present study is the first demonstration of an association between AD and MC using a case-control study design. It is unknown if the concurrent high incidence of eczema and MC is related, and this association deserves further investigation.
Subject:
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Ambulatory Care
Case-Control Studies
Child, Preschool
Female
Humans
Incidence
Indians, North American
Infant
Male
Molluscum Contagiosum
Molluscum Contagiosum Virus
Odds Ratio
Risk Factors

Source:
PLoS One. 2014; 9(7).;
Document Type:
Journal Article;
Place as Subject:
United States;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:036ebfae29bbf78e0f63748d11b11f826b8e52c470a12cc6f44c8e154bfc5b36
File Type:

Supporting Files

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