Molluscum Contagiosum in a Pediatric American Indian Population: Incidence and Risk Factors

McCollum, Andrea M.; Holman, Robert C.; Hughes, Christine M.; Mehal, Jason M.; Folkema, Arianne M.; Redd, John T.; Cheek, James E.; Damon, Inger K.; Reynolds, Mary G.

doi:10.1371/journal.pone.0103419

i

Molluscum Contagiosum in a Pediatric American Indian Population: Incidence and Risk Factors

Supporting Files Public Domain

Jul 29 2014
By McCollum, Andrea M. ; Holman, Robert C. ; Hughes, Christine M. ; ...

File Language:

English

Details

Alternative Title:

PLoS One
Personal Author:

McCollum, Andrea M. ; Holman, Robert C. ; Hughes, Christine M. ; Mehal, Jason M. ; Folkema, Arianne M. ; Redd, John T. ; Cheek, James E. ; Damon, Inger K. ; Reynolds, Mary G.
Description:

Background

Molluscum contagiosum virus (MCV) causes an innocuous yet persistent skin infection in immunocompetent individuals and is spread by contact with lesions. Studies point to atopic dermatitis (AD) as a risk factor for MCV infection; however, there are no longitudinal studies that have evaluated this hypothesis.

Methods

Outpatient visit data from fiscal years 2001–2009 for American Indian and Alaska Native (AI/AN) children were examined to describe the incidence of molluscum contagiosum (MC). We conducted a case-control study of patients <5 years old at an Indian Health Service (IHS) clinic to evaluate dermatological risk factors for infection.

Results

The incidence rate for MC in children <5 years old was highest in the West and East regions. MC cases were more likely to have a prior or co-occurring diagnosis of eczema, eczema or dermatitis, impetigo, and scabies (p<0.05) compared to controls; 51.4% of MC cases had a prior or co-occurring diagnosis of eczema or dermatitis.

Conclusions

The present study is the first demonstration of an association between AD and MC using a case-control study design. It is unknown if the concurrent high incidence of eczema and MC is related, and this association deserves further investigation.
Subjects:

Ambulatory Care Case-Control Studies Child, Preschool Female Humans Incidence Indians, North American Infant Male Molluscum Contagiosum Molluscum Contagiosum Virus Odds Ratio Risk Factors
Source:

PLoS One. 2014; 9(7).
Document Type:

Journal Article
Place as Subject:

United States
Volume:

9
Issue:

7
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:036ebfae29bbf78e0f63748d11b11f826b8e52c470a12cc6f44c8e154bfc5b36
Download URL:

https://stacks.cdc.gov/view/cdc/24772/cdc_24772_DS1.pdf
File Type:

[PDF - 247.09 KB ]

File Language:

English

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