U.S. flag An official website of the United States government.
Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

i

Normal serum IgE and IgG antibody levels in adult male Cynomolgus monkeys.

Public Domain


Details

  • Personal Author:
  • Description:
    A study of normal serum immunoglobulin-E (IgE) and immunoglobulin-G (IgG) antibody concentrations in Cynomolgus-monkeys was conducted. The purpose was to establish baseline values of IgG and IgE concentrations in the Cynomolgus-monkey sera using methods commonly utilized for determining these parameters in human sera. Sera from 44 adult male Cynomolgus-monkeys (Macaca-fascicularis) were analyzed for IgE using a radioimmunoassay technique and IgG using an immunochemistry analyzer. The mean and median IgE concentrations were 43.2 and 39.1 nanograms per milliliter (ng/ml), respectively. The mean and median IgG concentrations were 1563 and 1390 milligrams per deciliter (mg/dl), respectively. The 0 and 100 percentile IgE concentrations were 12.9 and 147.2ng/ml, respectively. The 0 and 100 percentile IgG concentrations were 930 and 2840mg/dl, respectively. The authors note that serum IgE and IgG concentrations in Cynomolgus-monkeys probably depend on the same factors that determine IgE and IgG concentrations in humans such as age, sex, heredity, allergy history, and recurrent or extant bacterial or parasitic infections. The measured IgE and IgG concentrations agree well with the range of values reported for humans and other monkey species. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    0023-6764
  • Document Type:
    Text
  • Genre:
    Journal Article
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Pages in Document:
    194-196
  • Volume:
    38
  • Issue:
    2
  • NIOSHTIC Number:
    nn:00184743
  • Citation:
    Lab Anim Sci 1988 Apr; 38(2):194-196
  • Federal Fiscal Year:
    1988
  • Peer Reviewed:
    True
  • Source Full Name:
    Laboratory Animal Science
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
  • Download URL:
  • File Type:
    Filetype[PDF - 168.02 KB ]
PREVIOUS
ON THIS PAGE
Details
CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
BACK TO TOP