Organolead compounds.

Details

• Description:
  The molecular structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures, uses, and producer and user data are provided for lead-naphthenate (50825291), tetramethyl-lead (75741), and tetraethyl-lead (78002) (TEL). These lead (7439921) compounds exert their toxic effects on the central nervous system and are accompanied by symptoms ranging from behavioral disorders and hyperagitation to convulsions and paralysis. TEL affects the liver, kidneys, pancreas, stomach, thyroid, lungs, heart, the endocrine system, thymus, adrenals, and testes. Tetramethyl-lead and TEL have been determined to be carcinogenic, while lead-naphthenate is neoplastic. TEL, an additive in motor fuel, accounts for much of the airborne lead that man breathes, although not in organic form. TEL can cause delirium, hallucinations, mania, convulsions, coma and death. Threshold limit values for tetramethyl-lead and TEL are given, with some other standards. (Contract No. 210-77-0120) [Description provided by NIOSH]
• Subjects:
  Carcinogens Digestive System Digestive System Diseases Hazardous Substances Kidney Diseases Lead Liver Metals Metals, Heavy Nervous System Diseases Occupational Health Safety Urogenital Diseases Urogenital System

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• Keywords:
  NIOSH-Contract; Contract-210-77-0120; Nervous-system-disorders; Organo-lead-compounds; Organo-metallic-compounds; Toxic-substances; Heavy-metals; Liver-disorders; Kidney-disorders; Stomach-disorders; Gastrointestinal-system-disorders; Carcinogens; Exposure-limits
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Report
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  276-286
• NIOSHTIC Number:
  nn:00075433
• Citation:
  NIOSH 1977 Oct; :276-286
• CAS Registry Number:
  Cyclohexanecarboxylic acid, lead salt (1:?) (CAS RN 50825-29-1) ; Lead (CAS RN 7439-92-1) ; Tetraethyllead (CAS RN 78-00-2) ; Tetramethyllead (CAS RN 75-74-1)
• Federal Fiscal Year:
  1978
• Peer Reviewed:
  False
• Source Full Name:
  Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/247451/cdc_247451_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]