Methyl ethyl ketone peroxide.

Details

• Description:
  This information profile on methyl-ethyl-ketone-peroxide (1338234) lists its molecular structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures and economic trends in production, uses, number of companies producing and using the substance, and the biological effects of exposure. Given orally, by inhalation, or by intraperitoneal injection, methyl-ethyl-ketone-peroxide causes hyperemia of the lungs with petechial or gross hemorrhage in mice and rats. Liver damage has been associated with subacute exposures. The compound also irritates eyes and skin. Acute, subchronic, and chronic effects of exposure are discussed. In humans chemical burns of the gastrointestinal tract, as well as residual scarring and structure of the esophagus were noted in an individual surviving ingestion of two ounces of a 60 percent solution. The threshold limit value is set at 0.2 ppm. (Contract No. 210-77-0120) [Description provided by NIOSH]
• Subjects:
  Digestive System Digestive System Diseases Hazardous Substances Irritants Liver Occupational Health Peroxides Plastics Respiratory Tract Diseases Safety
• Keywords:
  NIOSH-Contract; Contract-210-77-0120; Toxic-substances; Thresholds; Peroxides; Gastrointestinal-system-disorders; Plastics-industry; Synthetic-resins; Composites; Respiratory-system-disorders; Liver-disorders; Irritants
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Report
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  37-41
• NIOSHTIC Number:
  nn:00075410
• Citation:
  NIOSH 1977 Oct; :37-41
• CAS Registry Number:
  Methyl ethyl ketone peroxide (CAS RN 1338-23-4)
• Federal Fiscal Year:
  1978
• NORA Priority Area:
  Disease and Injury: Asthma and Chronic Obstructive Pulmonary Disease
• Peer Reviewed:
  False
• Source Full Name:
  Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/247431/cdc_247431_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]