Exposure to mixtures of airborne contaminants. Final progress report grant R01-OH-00472.

Details

• Personal Author:
  Smith FA
• Description:
  The effect of particulate and gaseous airborne pollutants was studied in Camm-Harty-guinea-pigs. Animals were exposed for 6 hours per day, 5 days per week for 16 weeks to 1.2 milligrams per cubic meter (mg/cu m) of fluorspar (7789755) dust of respirable size, or to 3.3mg/cu m of hydrogen-fluoride (7664393) (HF). The animals were maintained for up to 89 days after exposure. Both agents caused increases in the fluoride burden in the plasma, femur and feces. Exposure to HF also increased the number of free alveolar macrophages, while the incidence of patchy pneumonitis decreased. Pulmonary edema persisted for 2 days after exposure. All responses returned to normal after exposure was terminated and no further adverse effects were seen. The author recommends that fluoride containing pollutants in the workplace be characterized and that epidemiological studies be performed for populations living near fluoride emitting industries. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no pdf
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Biochemistry Laboratories Occupational Health Respiratory Tract Diseases Safety
• Keywords:
  NIOSH-Grant; Biochemistry; Physiology; Laboratory-animals; Air-contamination; Pulmonary-system-disorders
• Series:
  Grant Final Reports
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-25
• NIOSHTIC Number:
  nn:00112242
• NTIS Accession Number:
  PB88247697
• Citation:
  Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, R01-OH-000472, 1977 Apr; :1-25
• Contact Point Address:
  Radiation Biology & Biophysics University of Rochester Dept of Rad Biol & Biophysics Rochester, N Y 14642
• CAS Registry Number:
  Calcium fluoride (CAS RN 7789-75-5) ; Hydrofluoric acid (CAS RN 7664-39-3)
• Federal Fiscal Year:
  1977
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of Rochester, Rochester, New York
• Peer Reviewed:
  False
• Start Date:
  19740501
• Source Full Name:
  National Institute for Occupational Safety and Health
• End Date:
  19790430
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/246040/cdc_246040_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]