Relation of smoking to neoplasia in asbestos workers (final report).

Details

• Personal Author:
  Selikoff IJ
• Description:
  A cohort of 17,800 male asbestos (1332214) insulation workers was compared with a control group of 73,763 males to evaluate the combined effects of cigarette smoking and exposure to asbestos dust in relation to death from lung cancer and chronic infectious pulmonary diseases. The relationship to cancer other than mesothelioma and lung cancer and the degree to which occupational exposure to asbestos dust increases total death rates from all cancers combined also was studied. Data were collected for the period between January 1, 1967 and December 31, 1976. A strong synergistic effect between asbestos dust and cigarette smoke exposure and the risk of lung cancer was indicated. Among asbestos workers, former cigarette smokers had substantially lower death rates than smokers who maintained the habit. Cigarette smoking also increased the risk of death from asbestosis. Exposure to asbestos dust resulted in increased death rates from lung cancer, mesothelioma, and asbestosis. Exposure to the dust also increased death rates from cancers of the colon and rectum, esophagus, kidney, and the group comprising the larynx, pharynx, and buccal cavity. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Asbestos Carcinogens Dust Inorganic Chemicals Mortality Occupational Health Particulate Matter Respiratory Tract Diseases Safety Smokers

  More +
• Keywords:
  NIOSH-Grant; Pulmonary-system-disorders; Asbestos-fibers; Airborne-dusts; Carcinogenesis; Respiratory-system-disorders; Mortality-data; Smoking; Physiological-effects; Asbestos-products; Insulation-workers
• Series:
  Grant Final Reports
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-25
• NIOSHTIC Number:
  nn:00091886
• Citation:
  Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, R01-OH-000320, 1979 May; :1-25
• Contact Point Address:
  Community Medicine Mount Sinai School of Medicine Fifth Avenue and 100 Street New York, N Y 10029
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4)
• Federal Fiscal Year:
  1979
• Performing Organization:
  Mount Sinai School of Medicine, New York
• Peer Reviewed:
  False
• Start Date:
  19700501
• Source Full Name:
  National Institute for Occupational Safety and Health
• End Date:
  19790630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/246037/cdc_246037_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]