An investigation of mortality from cancer and other causes of death among workers employed at an East Texas chemical plant.

Details

• Personal Author:
  Beaumont, James J. ; Halperin, William E. ; Sweeney, Marie H. ; Waxweiler, Richard J. ; Beaumont, James J. ; Halperin, William E. ; Sweeney, Marie H. ; Waxweiler, Richard J.
• Description:
  A historical prospective mortality study of chemical workers was conducted. The purpose of the study was to evaluate a suspected increase in deaths due to brain cancer and multiple myeloma. The cohort consisted of 2510 males who worked for at least 1 day at a chemical factory in East Texas between January 1, 1952 and December 31, 1977. The facility's major product was tetraethyllead (78002). The cohort was traced through company, union, Social Security Administration, Internal Revenue Service, and state records. Death certificates were obtained from state vital statistics offices. The observed mortality was compared with predicted rates for all United States males. Overall mortality for all causes of death was lower than that expected, 156 versus 211.14. The number of deaths for all cancers was 38 versus 36.95 expected. Insignificant increases in deaths due to brain cancer (4 observed versus 1.88 expected), respiratory system cancer (14 observed versus 12.47 expected), and colorectal cancer (5 observed versus 3.73 expected) occurred. The authors conclude that no statistically significant increase in site specific mortality from cancer occurred. The small excess observed for brain and other cancers may have been due to chance associations. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Epidemiology Lead Manufacturing And Industrial Facilities Metals, Heavy Mortality Neoplasms Occupational Health Risk Assessment Safety
• Keywords:
  NIOSH-Author; Chemical-manufacturing-industry; Epidemiology; Mortality-surveys; Heavy-metals; Organo-lead-compounds; Cancer-rate; Risk-analysis
• Document Type:
  Text
• Genre:
  Case Studies ; Case Studies
• Place as Subject:
  Ohio ; OSHA Region 5 ; OSHA Region 6 ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Pages in Document:
  1-19
• NIOSHTIC Number:
  nn:00146787
• NTIS Accession Number:
  PB85220945
• Citation:
  NIOSH 1984 Oct; :1-19
• CAS Registry Number:
  Tetraethyllead (CAS RN 78-00-2) ; Tetraethyllead (CAS RN 78-00-2)
• Federal Fiscal Year:
  1985
• Peer Reviewed:
  False
• Source Full Name:
  Robert A. Taft Laboratories, NIOSH, U.S. Department of Health and Human Services, Cincinnati, Ohio, 19 pages, 15 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/245681/cdc_245681_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]