Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2008.130910
Personal Author:
Li, Xianbin ; Zhang, Zhong ; Yu, Ailian ; Ho, Simon Y. W. ; Carr, Michael J. ; ... More +
Li, Xianbin ; Zhang, Zhong ; Yu, Ailian ; Ho, Simon Y. W. ; Carr, Michael J. ; Zheng, Weimin ; Zhang, Yanzhou ; Zhu, Chaodong ; Lei, Fumin ; Shi, Weifeng ; Less -
Description:
An understanding of the global migration dynamics of highly pathogenic avian influenza A(H5N1) virus is helpful for surveillance and disease prevention. To characterize the migration network of this virus, we used genetic analysis, which supported a global persistence model in which each of 9 regions acts to some extent as a source. Siberia is the major hub for the dispersal of the virus. Southeast Asia and Africa are major sources of genetically and antigenically novel strains. We found evidence of local persistence of the virus in Southeast Asia and Africa, which is rare for human influenza A viruses. The differences in migration dynamics between avian and human influenza viruses might help with the design of region-specific surveillance efforts and the selection of vaccine candidates.
Subject:
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Avian Influenza
H5N1
Influenza
Migration Network
Persistence
Research
Source
Viruses

Source:
Emerg Infect Dis. 20(8):1287-1295. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:f43564810d87ba8fdf9da44d69cc75a6014bbe2a04877ae969d74a0f5d9bd4f6
File Type:

Supporting Files

• 	13-0910-Techapp-s1.pdf	pdf
  	13-0910.nxml	txt
  	license.txt	txt
  	13-0910-F1.gif	gif
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