Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1705.101707
Personal Author:
McMullen, Allison R. ; May, Fiona J. ; Li, Li ; Guzman, Hilda ; Bueno, Rudy ; ... More +
McMullen, Allison R. ; May, Fiona J. ; Li, Li ; Guzman, Hilda ; Bueno, Rudy ; Dennett, James A. ; Tesh, Robert B. ; Barrett, Alan D.T. Less -
Description:
Previous studies of North American isolates of West Nile virus (WNV) during 1999-2005 suggested that the virus had reached genetic homeostasis in North America. However, genomic sequencing of WNV isolates from Harris County, Texas, during 2002-2009 suggests that this is not the case. Three new genetic groups have been identified in Texas since 2005. Spread of the southwestern US genotype (SW/WN03) from the Arizona/Colorado/northern Mexico region to California, Illinois, New Mexico, New York, North Dakota, and the Texas Gulf Coast demonstrates continued evolution of WNV. Thus, WNV continues to evolve in North America, as demonstrated by selection of this new genotype. Continued surveillance of the virus is essential as it continues to evolve in the New World.
Subject:
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Amino Acid Substitution
Animals
Cercopithecus Aethiops
Evolution, Molecular
Genetic Variation
Genotype
Phylogeny
Research
RNA, Viral
Selection, Genetic
Vero Cells
West Nile Fever

Source:
Emerg Infect Dis. 17(5):785-793.
Document Type:
Journal Article
Funding:
AI 067847/AI/NIAID NIH HHS/United States ; AI 07526/AI/NIAID NIH HHS/United States ; N01-AI25489/AI/NIAID NIH HHS/United States ; N01-AI30027/AI/NIAID NIH HHS/United States
AI 067847/AI/NIAID NIH HHS/United States ; AI 07526/AI/NIAID NIH HHS/United States ; N01-AI25489/AI/NIAID NIH HHS/United States ; N01-AI30027/AI/NIAID NIH HHS/United States Less -
Place as Subject:
North America
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:652025f0ceac6c1666c01464b5950b070fb30132f4d8ccc00842d954415bc733
File Type:

Supporting Files

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