Workshop on irritant contact dermatitis.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  The causes, nature, and pathomechanisms of irritant contact dermatitis (ICD) were discussed in a workshop format. The presentations dealt with the following issues: clinical ICD syndromes; a comparison of allergic contact dermatitis (ACD) and ICD; the magnitude of the problem of ICD; the basic features and definitions of ICD; cellular immunologic characteristics of ICD; dermal antigen presenting cells and macrophages; the role of keratinocytes; T-lymphocyte function in ICD; cutaneous signals that initiate sensitivity and tolerance; barrier initiated mechanisms in ICD; effects on stratum corneum barrier function; electrical creation of aqueous pathways across skin and absorption; immunologic consequences of barrier perturbation; role of neuropeptides; role of cytokines; role of prostaglandins and other lipid mediators; in-vivo and in-vitro model systems for ICD; human models; cell culture techniques; transgenic mouse models; the prevention of ICD; and molecular mechanisms of ICD. [Description provided by NIOSH]
• Subjects:
  Biochemistry Dermatitis Hypersensitivity Immune System Occupational Health Safety Skin Skin Diseases
• Keywords:
  Allergic-dermatitis; Contact-dermatitis; Skin-disorders; Pathogenesis; Immunologic-disorders; Cell-function; Skin-sensitivity; Skin-tests; Skin-irritants; Biochemistry
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-76
• NIOSHTIC Number:
  nn:00234551
• Citation:
  Bethesda, Maryland, March 25-26, 1996, National Institute of Arthritis and Musculoskeletal and Skin Diseases, and the National Institute for Occupational Safety and Health, 1996 Mar; 1-:76
• Federal Fiscal Year:
  1996
• Peer Reviewed:
  False
• Source Full Name:
  Bethesda, Maryland, March 25-26, 1996, National Institute of Arthritis and Musculoskeletal and Skin Diseases, and the National Institute for Occupational Safety and Health, 76 pages, 189 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/243522/cdc_243522_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]