Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1705.100754
Personal Author:
Kerdsin, Anusak ; Dejsirilert, Surang ; Puangpatra, Parichart ; Sripakdee, Saowalak ; Chumla, Koranan ; ... More +
Kerdsin, Anusak ; Dejsirilert, Surang ; Puangpatra, Parichart ; Sripakdee, Saowalak ; Chumla, Koranan ; Boonkerd, Nitsara ; Polwichai, Pitimol ; Tanimura, Susumu ; Takeuchi, Dan ; Nakayama, Tatsuya ; Nakamura, Shota ; Akeda, Yukihiro ; Gottschalk, Marcelo ; Sawanpanyalert, Pathom ; Oishi, Kazunori Less -
Description:
To examine associations between clinical features of Streptococcus suis serotype 2 infections in humans in Thailand and genotypic profiles of isolates, we conducted a retrospective study during 2006-2008. Of 165 patients for whom bacterial cultures of blood, cerebrospinal fluid, or both were positive for S. suis serotype 2, the major multilocus sequence types (STs) found were ST1 (62.4%) and ST104 (25.5%); the latter is unique to Thailand. Clinical features were examined for 158 patients. Infections were sporadic; case-fatality rate for adults was 9.5%, primarily in northern Thailand. Disease incidence peaked during the rainy season. Disease was classified as meningitis (58.9%) or nonmeningitis (41.1%, and included sepsis [35.4%] and others [5.7%]). Although ST1 strains were significantly associated with the meningitis category (p<0.0001), ST104 strains were significantly associated with the nonmeningitis category (p<0.0001). The ST1 and ST104 strains are capable of causing sepsis, but only the ST1 strains commonly cause meningitis.
Subjects:
[+]
Adolescent Adult Aged Aged, 80 And Over Cluster Analysis Female Genotype Humans Male Middle Aged Molecular Epidemiology Multilocus Sequence Typing Phylogeography Retrospective Studies Seasons Streptococcal Infections Young Adult
Source:
Emerg Infect Dis. 17(5):835-842.
Document Type:
Journal Article
Place as Subject:
Thailand
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:ec83c920ef994865ed38728fa0c5db93f2f4df31a11b4f8bf7cbeb4b32564019
Download URL:
https://stacks.cdc.gov/view/cdc/24344/cdc_24344_DS1.pdf
File Type:

Supporting Files

• 	10-0754-F1.gif	gif
  	10-0754-F1.jpg	jpeg
  	10-0754-F2.gif	gif
  	10-0754-F2.jpg	jpeg
  	10-0754_finalR.nxml	txt
  	license.txt	txt

More +